BACKGROUND: Hyperlipidemia is a major risk factor for cardiovascular disease. Recent reports showed a possible association between periodontal disease and an increased risk for cardiovascular disease. The aim of this study was to evaluate whether hyperlipidemia has any influence on periodontal status. METHODS: Fifty-one subjects with hyperlipidemia and 47 normolipidemic subjects participated in this study. Biochemical parameters, including plasma triglyceride, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels, and periodontal parameters, including plaque index (PI), probing depth (PD), clinical attachment level (CAL), and percentage of sites with bleeding on probing (BOP [%]), were evaluated. RESULTS: The mean values of PI, PD, CAL, and BOP (%) for the hyperlipidemic group were significantly higher than those for the control group. Plasma triglyceride, total cholesterol, and LDL-C levels were significantly and positively associated with PI, PD, BOP (%), and CAL. HDL-C was significantly, but negatively, associated with CAL. Plasma triglyceride level was significantly associated with PD and BOP (%) after further analyses. CONCLUSIONS: The results of our study showed that patients with mild or moderate hyperlipidemia manifested higher values of periodontal parameters compared to normolipidemic individuals. Further studies are needed to determine the effect of hyperlipidemia on periodontal disease.
BACKGROUND:Hyperlipidemia is a major risk factor for cardiovascular disease. Recent reports showed a possible association between periodontal disease and an increased risk for cardiovascular disease. The aim of this study was to evaluate whether hyperlipidemia has any influence on periodontal status. METHODS: Fifty-one subjects with hyperlipidemia and 47 normolipidemic subjects participated in this study. Biochemical parameters, including plasma triglyceride, total cholesterol, low-density lipoprotein cholesterol (LDL-C), and high-density lipoprotein cholesterol (HDL-C) levels, and periodontal parameters, including plaque index (PI), probing depth (PD), clinical attachment level (CAL), and percentage of sites with bleeding on probing (BOP [%]), were evaluated. RESULTS: The mean values of PI, PD, CAL, and BOP (%) for the hyperlipidemic group were significantly higher than those for the control group. Plasma triglyceride, total cholesterol, and LDL-C levels were significantly and positively associated with PI, PD, BOP (%), and CAL. HDL-C was significantly, but negatively, associated with CAL. Plasma triglyceride level was significantly associated with PD and BOP (%) after further analyses. CONCLUSIONS: The results of our study showed that patients with mild or moderate hyperlipidemia manifested higher values of periodontal parameters compared to normolipidemic individuals. Further studies are needed to determine the effect of hyperlipidemia on periodontal disease.
Authors: Alliny de Souza Bastos; Dana T Graves; Ana Paula de Melo Loureiro; Carlos Rossa Júnior; Sâmia Cruz Tfaile Corbi; Fausto Frizzera; Raquel Mantuaneli Scarel-Caminaga; Niels Olsen Câmara; Oelisoa M Andriankaja; Meire I Hiyane; Silvana Regina Perez Orrico Journal: J Diabetes Complications Date: 2016-07-21 Impact factor: 2.852
Authors: X L Zhu; W J Li; X E Wang; W L Song; L Xu; L Zhang; X H Feng; R F Lu; D Shi; H X Meng Journal: Beijing Da Xue Xue Bao Yi Xue Ban Date: 2022-02-18
Authors: Alliny S Bastos; Dana T Graves; Ana Paula de Melo Loureiro; Carlos Rossa Júnior; Dulcinéia Saes Parra Abdalla; Tanize do Espírito Santo Faulin; Niels Olsen Câmara; Oelisoa M Andriankaja; Silvana R P Orrico Journal: J Clin Endocrinol Metab Date: 2012-05-07 Impact factor: 5.958