Literature DB >> 19184052

Do not rush into operating and just observe actively if you are not sure about the diagnosis of appendicitis.

Yusuf Hakan Cavuşoğlu1, Derya Erdoğan, Ayşe Karaman, Mustafa K Aslan, Ibrahim Karaman, Ozden C Tütün.   

Abstract

PURPOSE: The aim of this study was to determine whether the admission and active observation of children where the diagnosis of acute appendicitis is uncertain is a safe and effective way to improve the diagnostic accuracy of appendicitis and safely reduce the incidence of negative laparotomies without increasing complications.
METHODS: We performed a retrospective cohort study of children who presented with a complaint of right lower quadrant pain and were hospitalized with a diagnosis of appendicitis or suspected appendicitis from 1 January to 31 December 2007.
RESULTS: A total of 569 patients were included in the study. The mean age was 9.5 +/- 3.2 (range 1.1-17) years. The number of patients directly operated on with a diagnosis of appendicitis was 186 (32%) from the total of 575 while 389 patients (68%) were observed in the surgical ward as the examination and/or investigation findings were equivocal. Of the 383 patients admitted for observation, 173 (45%) were operated on with a suspicion of appendicitis after 14.4 +/- 6.7 h while 210 (55%) were discharged after 1.1 +/- 1.2 days as there seemed to have no surgical problem. Our total negative appendectomy rate was 4% (14/350) and total perforation rate was 37.4% (131/350). The patients operated on directly and those operated on after observation were similar, and there was no difference for the preoperative duration of symptom, histopathological diagnosis, postoperative complication rate, postoperative inpatient days and hospital charges. Total hospitalization duration was significantly longer and the hospital charges significantly higher in the negative appendectomy group.
CONCLUSION: Both the features and results and the complication rates and costs of the group operated on after observation were the same as the directly operated on group. However, patients undergoing a negative appendectomy stayed as inpatients longer than only observation patients with higher treatment charges. We could therefore decrease the negative appendectomy rate, the associated cost and duration of hospitalization without causing extra complications if we observe and investigate patients with right lower quadrant pain with a doubtful diagnosis and did not operate on them directly.

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Mesh:

Year:  2009        PMID: 19184052     DOI: 10.1007/s00383-009-2331-0

Source DB:  PubMed          Journal:  Pediatr Surg Int        ISSN: 0179-0358            Impact factor:   1.827


  17 in total

1.  Balancing the normal appendectomy rate with the perforated appendicitis rate: implications for quality assurance.

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Journal:  Am Surg       Date:  1992-04       Impact factor: 0.688

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Authors:  D Brenner; C Elliston; E Hall; W Berdon
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Journal:  JAMA       Date:  2001-10-10       Impact factor: 56.272

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5.  Ultrasonography and limited computed tomography in the diagnosis and management of appendicitis in children.

Authors:  B M Garcia Peña; K D Mandl; S J Kraus; A C Fischer; G R Fleisher; D P Lund; G A Taylor
Journal:  JAMA       Date:  1999-09-15       Impact factor: 56.272

6.  Guideline for Prevention of Surgical Site Infection, 1999. Centers for Disease Control and Prevention (CDC) Hospital Infection Control Practices Advisory Committee.

Authors:  A J Mangram; T C Horan; M L Pearson; L C Silver; W R Jarvis
Journal:  Am J Infect Control       Date:  1999-04       Impact factor: 2.918

7.  Computed tomography and ultrasonography do not improve and may delay the diagnosis and treatment of acute appendicitis.

Authors:  S L Lee; A J Walsh; H S Ho
Journal:  Arch Surg       Date:  2001-05

8.  Indications for operation in suspected appendicitis and incidence of perforation.

Authors:  R Andersson; A Hugander; A Thulin; P O Nyström; G Olaison
Journal:  BMJ       Date:  1994-01-08

9.  An evidenced-based clinical pathway for acute appendicitis decreases hospital duration and cost.

Authors:  B W Warner; R M Kulick; M M Stoops; S Mehta; M Stephan; U R Kotagal
Journal:  J Pediatr Surg       Date:  1998-09       Impact factor: 2.545

10.  The risk of perforation when children with possible appendicitis are observed in the hospital.

Authors:  S E Dolgin; A R Beck; P I Tartter
Journal:  Surg Gynecol Obstet       Date:  1992-10
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  8 in total

1.  Increased incidence of negative appendectomy in childhood obesity.

Authors:  Balazs Kutasy; Manuela Hunziker; Ganapathy Laxamanadass; Prem Puri
Journal:  Pediatr Surg Int       Date:  2010-10       Impact factor: 1.827

Review 2.  [Strategy for avoidance of negative appendectomies].

Authors:  M N Wente; H Waleczek
Journal:  Chirurg       Date:  2009-07       Impact factor: 0.955

3.  Negative Appendectomy: an Audit of Resident-Performed Surgery. How Can Its Incidence Be Minimized?

Authors:  Mohit Kumar Joshi; Richa Joshi; Shaan E Alam; Sarla Agarwal; Sunil Kumar
Journal:  Indian J Surg       Date:  2014-04-09       Impact factor: 0.656

4.  Application with repeated serum biomarkers in pediatric appendicitis in clinical surgery.

Authors:  Han-Ping Wu; Yun-Ching Fu
Journal:  Pediatr Surg Int       Date:  2009-11-18       Impact factor: 1.827

5.  Negative Appendectomy Rate and Risk Factors That Influence Improper Diagnosis at King Abdulaziz University Hospital.

Authors:  Yara F Alhamdani; Hisham A Rizk; Mohammed R Algethami; Asma M Algarawi; Roia H Albadawi; Sofana N Faqih; Elaf H Ahmed; Ohud J Abukammas
Journal:  Mater Sociomed       Date:  2018-10

6.  Diagnostic performance of abdominal point of care ultrasound performed by an emergency physician in acute right iliac fossa pain.

Authors:  Jean-Eudes Bourcier; Emeric Gallard; Jean-Philippe Redonnet; Magali Majourau; Dominique Deshaie; Jean-Marie Bourgeois; Didier Garnier; Thomas Geeraerts
Journal:  Crit Ultrasound J       Date:  2018-11-23

7.  Meta-analysis of the therapeutic effects of antibiotic versus appendicectomy for the treatment of acute appendicitis.

Authors:  Zhi-Hua Liu; Chao Li; Xing-Wei Zhang; Liang Kang; Jian-Ping Wang
Journal:  Exp Ther Med       Date:  2014-02-25       Impact factor: 2.447

8.  Calprotectin could be a potential biomarker for acute appendicitis.

Authors:  Peter C Ambe; Daniel Gödde; Lars Bönicke; Marios Papadakis; Stephan Störkel; Hubert Zirngibl
Journal:  J Transl Med       Date:  2016-04-27       Impact factor: 5.531

  8 in total

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