Literature DB >> 19182793

Programmed subcellular release for studying the dynamics of cell detachment.

Bridget Wildt1, Denis Wirtz, Peter C Searson.   

Abstract

Cell detachment is central to a broad range of physiopathological changes, but there are no quantitative methods to study this process. Here we report programmed subcellular release, a method for spatially and temporally controlled cellular detachment, and present quantitative results of the detachment dynamics of 3T3 fibroblasts at the subcellular level.

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Year:  2009        PMID： 19182793      PMCID： PMC2882093          DOI： 10.1038/nmeth.1299

Source DB:  PubMed          Journal:  Nat Methods        ISSN： 1548-7091            Impact factor:   28.547


  15 in total

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9.  Cell spreading and lamellipodial extension rate is regulated by membrane tension.

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Journal:  J Cell Biol       Date:  2000-01-10       Impact factor: 10.539

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  12 in total

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6.  Triggering cell detachment from patterned electrode arrays by programmed subcellular release.

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Review 7.  The physics of cancer: the role of physical interactions and mechanical forces in metastasis.

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8.  Cell-Matrix De-Adhesion Dynamics Reflect Contractile Mechanics.

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9.  The perinuclear actin cap in health and disease.

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