Literature DB >> 19181814

Creation of a large deletion mutant of Campylobacter jejuni reveals that the lipooligosaccharide gene cluster is not required for viability.

Gemma L Marsden1, Jianjun Li, Paul H Everest, Andrew J Lawson, Julian M Ketley.   

Abstract

Deletion of the lipooligosaccharide biosynthesis region (Cj1132c to Cj1152c) from the genome of Campylobacter jejuni NCTC11168 shows that the core is not required for viability. The mutant was attenuated for growth and has increased sensitivity to antibiotics and detergents. Natural transformation and invasion of cultured host cells was abolished.

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Year:  2009        PMID: 19181814      PMCID: PMC2655488          DOI: 10.1128/JB.01397-08

Source DB:  PubMed          Journal:  J Bacteriol        ISSN: 0021-9193            Impact factor:   3.490


  24 in total

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Review 3.  Pathogenesis of enteric infection by Campylobacter.

Authors:  Julian M Ketley
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5.  Cloning, mutation and distribution of a putative lipopolysaccharide biosynthesis locus in Campylobacter jejuni.

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Review 6.  Association between Campylobacter infection and Guillain-Barré syndrome.

Authors:  B M Allos
Journal:  J Infect Dis       Date:  1997-12       Impact factor: 5.226

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Authors:  Christine M Szymanski; Frank St Michael; Harold C Jarrell; Jianjun Li; Michel Gilbert; Suzon Larocque; Evgeny Vinogradov; Jean-Robert Brisson
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8.  Chemical structures of the core region of Campylobacter jejuni O:3 lipopolysaccharide and an associated polysaccharide.

Authors:  G O Aspinall; C M Lynch; H Pang; R T Shaver; A P Moran
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9.  The structures of the lipooligosaccharide and capsule polysaccharide of Campylobacter jejuni genome sequenced strain NCTC 11168.

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Authors:  E McSweegan; R I Walker
Journal:  Infect Immun       Date:  1986-07       Impact factor: 3.441

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4.  Helicobacter pylori lipopolysaccharide is synthesized via a novel pathway with an evolutionary connection to protein N-glycosylation.

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  5 in total

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