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Literature DB >> 19181807

An RNA hairpin sequesters the ribosome binding site of the homing endonuclease mobE gene.

Abstract

Previous transcript mapping of the bacteriophage Aeh1 nrd operon revealed a predicted RNA hairpin upstream of the homing endonuclease mobE gene. We enzymatically mapped the hairpin, showing that the mobE ribosome binding site is sequestered. Cloning of the hairpin upstream of lacZ resulted in reduced beta-galactosidase activity, consistent with translational regulation.

Entities: Gene Species

Mesh：

Substances：

Year: 2009 PMID： 19181807 PMCID： PMC2655525 DOI： 10.1128/JB.01751-08

Source DB: PubMed Journal: J Bacteriol ISSN： 0021-9193 Impact factor: 3.490

26 in total

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Review 2. Inteins: structure, function, and evolution.

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Authors: M Sharma; R L Ellis; D M Hinton
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8. Insertion of a homing endonuclease creates a genes-in-pieces ribonucleotide reductase that retains function.

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2. Assembly of a fragmented ribonucleotide reductase by protein interaction domains derived from a mobile genetic element.

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Journal: Nucleic Acids Res Date: 2010-10-23 Impact factor: 16.971