Literature DB >> 19178279

Disulfide-linked, gold nanoparticle based reagent for detecting small molecular weight thiols.

Suzanne Durocher1, Asad Rezaee, Caroline Hamm, Chitra Rangan, Silvia Mittler, Bulent Mutus.   

Abstract

Disulfide-linked gold nanoparticles (AuNP) were synthesized by reacting dithiobis[succinimidylpropionate] (DSP) coated nanoparticles with glutathione disulfide. AuNP-cross-linking was monitored by the red shift and broadening of the AuNP's localized surface plasmon absorption resonance (LSPR) spectrum. The exposure of the disulfide-linked AuNPs to a variety of free thiols with systematically varying molecular weight revealed a AuNP-disulfide stability to reduction by thiols up to a critical molecular weight, M(c), of >300 Da thus making the disulfide-linked AuNP the first reagent that can discriminate thiols based on their size.

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Year:  2009        PMID: 19178279     DOI: 10.1021/ja808548x

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN: 0002-7863            Impact factor:   15.419


  9 in total

1.  Non-protein thiol imaging and quantification in live cells with a novel benzofurazan sulfide triphenylphosphonium fluorogenic compound.

Authors:  Yang Yang; Xiangming Guan
Journal:  Anal Bioanal Chem       Date:  2017-03-29       Impact factor: 4.142

2.  Benzofurazan sulfides for thiol imaging and quantification in live cells through fluorescence microscopy.

Authors:  Yinghong Li; Yang Yang; Xiangming Guan
Journal:  Anal Chem       Date:  2012-07-26       Impact factor: 6.986

3.  Rapid and thiol-specific high-throughput assay for simultaneous relative quantification of total thiols, protein thiols, and nonprotein thiols in cells.

Authors:  Yang Yang; Xiangming Guan
Journal:  Anal Chem       Date:  2014-12-11       Impact factor: 6.986

Review 4.  Metallic Nanostructures Based on DNA Nanoshapes.

Authors:  Boxuan Shen; Kosti Tapio; Veikko Linko; Mauri A Kostiainen; Jari Jussi Toppari
Journal:  Nanomaterials (Basel)       Date:  2016-08-10       Impact factor: 5.076

5.  Magnetic Fe₃O₄-Based Sandwich-Type Biosensor Using Modified Gold Nanoparticles as Colorimetric Probes for the Detection of Dopamine.

Authors:  Zhiyong Wang; Yanyan Bai; Wenchao Wei; Ning Xia; Yuhui Du
Journal:  Materials (Basel)       Date:  2013-12-05       Impact factor: 3.623

6.  Nitrogen-Doped Carbon Nanoparticles Derived from Silkworm Excrement as On⁻Off⁻On Fluorescent Sensors to Detect Fe(III) and Biothiols.

Authors:  Xingchang Lu; Chen Liu; Zhimin Wang; Junyi Yang; Mengjing Xu; Jun Dong; Ping Wang; Jiangjiang Gu; Feifei Cao
Journal:  Nanomaterials (Basel)       Date:  2018-06-17       Impact factor: 5.076

Review 7.  Phytoantioxidant Functionalized Nanoparticles: A Green Approach to Combat Nanoparticle-Induced Oxidative Stress.

Authors:  Acharya Balkrishna; Ashwani Kumar; Vedpriya Arya; Akansha Rohela; Rachna Verma; Eugenie Nepovimova; Ondrej Krejcar; Dinesh Kumar; Naveen Thakur; Kamil Kuca
Journal:  Oxid Med Cell Longev       Date:  2021-10-26       Impact factor: 6.543

Review 8.  Thiol reactive probes and chemosensors.

Authors:  Hanjing Peng; Weixuan Chen; Yunfeng Cheng; Lovemore Hakuna; Robert Strongin; Binghe Wang
Journal:  Sensors (Basel)       Date:  2012-11-19       Impact factor: 3.576

9.  Dithiol-Induced Oligomerization of Thiol-Protected Gold Nanoclusters.

Authors:  Karolina Sokolowska; Eero Hulkko; Lauri Lehtovaara; Tanja Lahtinen
Journal:  J Phys Chem C Nanomater Interfaces       Date:  2018-05-17       Impact factor: 4.126

  9 in total

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