| Literature DB >> 19178158 |
Wayne Pilgrim1, Paul V Murphy.
Abstract
Bacterial glycolipids containing either alpha-glucuronic acid or alpha-galacturonic acid residues have an important role in the innate-type immune response to gram-negative bacteria. Synthesis of closely related compounds, including a novel alpha-SO(2) glycolipid mimetic, is described from carbohydrate precursors where anomerization is a key step. Very high stereoselectivites (>97:3 in favor of alpha) were observed from O-glycoside precursors.Entities:
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Year: 2009 PMID： 19178158 DOI： 10.1021/ol802915h
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005