| Literature DB >> 19166346 |
Abstract
The optically pure epoxy acetal was converted to the protected guanidino alcohol by reaction with NaN(3) in DMF, hydrogenation of the azide, and reaction of the amine with MeSC(NBoc)NHBoc, AgNO(3), and Et(3)N. Treatment of the protected guanidino alcohol with 9:1 CDCl(3)/TFA afforded monanchorin, whose absolute stereochemistry was assigned as shown.Entities:
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Year: 2009 PMID： 19166346 PMCID： PMC2661423 DOI： 10.1021/ol802981h
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005