Literature DB >> 19165578

A turning point for blood-brain barrier modeling.

Sean Ekins1, Alexander Tropsha.   

Abstract

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Year:  2009        PMID： 19165578     DOI： 10.1007/s11095-009-9832-3

Source DB:  PubMed          Journal:  Pharm Res        ISSN： 0724-8741            Impact factor:   4.200


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  4 in total

1.  Effect of selection of molecular descriptors on the prediction of blood-brain barrier penetrating and nonpenetrating agents by statistical learning methods.

Authors:  Hu Li; Chun Wei Yap; Choong Yong Ung; Ying Xue; Zhi Wei Cao; Yu Zong Chen
Journal:  J Chem Inf Model       Date:  2005 Sep-Oct       Impact factor: 4.956

2.  Combinatorial QSAR modeling of chemical toxicants tested against Tetrahymena pyriformis.

Authors:  Hao Zhu; Alexander Tropsha; Denis Fourches; Alexandre Varnek; Ester Papa; Paola Gramatica; Tomas Oberg; Phuong Dao; Artem Cherkasov; Igor V Tetko
Journal:  J Chem Inf Model       Date:  2008-03-01       Impact factor: 4.956

3.  QSAR modeling of the blood-brain barrier permeability for diverse organic compounds.

Authors:  Liying Zhang; Hao Zhu; Tudor I Oprea; Alexander Golbraikh; Alexander Tropsha
Journal:  Pharm Res       Date:  2008-06-14       Impact factor: 4.200

4.  New predictive models for blood-brain barrier permeability of drug-like molecules.

Authors:  Sandhya Kortagere; Dmitriy Chekmarev; William J Welsh; Sean Ekins
Journal:  Pharm Res       Date:  2008-04-16       Impact factor: 4.200
  4 in total
  3 in total

1.  Chemical space: missing pieces in cheminformatics.

Authors:  Sean Ekins; Rishi R Gupta; Eric Gifford; Barry A Bunin; Chris L Waller
Journal:  Pharm Res       Date:  2010-08-04       Impact factor: 4.200

Review 2.  Molecular determinants of blood-brain barrier permeation.

Authors:  Werner J Geldenhuys; Afroz S Mohammad; Chris E Adkins; Paul R Lockman
Journal:  Ther Deliv       Date:  2015-08-25

3.  Towards Deep Neural Network Models for the Prediction of the Blood-Brain Barrier Permeability for Diverse Organic Compounds.

Authors:  Eugene V Radchenko; Alina S Dyabina; Vladimir A Palyulin
Journal:  Molecules       Date:  2020-12-13       Impact factor: 4.411
  3 in total

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