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Literature DB >> 19164810

Vascular endothelial growth factor.

Abstract

Vascular endothelial growth factor (VEGF, VEGF-A) is a major regulator of physiological and pathological angiogenesis. Several VEGF inhibitors have been approved by the FDA for the treatment of advanced cancer and neovascular age-related macular degeneration. This brief review provides a historic account of the challenges associated with the discovery of VEGF and the early steps in elucidating the role of this molecule in the regulation of angiogenesis.

Entities: Disease Gene

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Year: 2009 PMID： 19164810 DOI： 10.1161/ATVBAHA.108.179663

Source DB: PubMed Journal: Arterioscler Thromb Vasc Biol ISSN： 1079-5642 Impact factor: 8.311

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Cited

157 in total

1. Evolution of the VEGF-regulated vascular network from a neural guidance system.

Authors: Sreenivasan Ponnambalam; Mario Alberghina
Journal: Mol Neurobiol Date: 2011-01-28 Impact factor: 5.590

Review 2. The mouse retina as an angiogenesis model.

Authors: Andreas Stahl; Kip M Connor; Przemyslaw Sapieha; Jing Chen; Roberta J Dennison; Nathan M Krah; Molly R Seaward; Keirnan L Willett; Christopher M Aderman; Karen I Guerin; Jing Hua; Chatarina Löfqvist; Ann Hellström; Lois E H Smith
Journal: Invest Ophthalmol Vis Sci Date: 2010-06 Impact factor: 4.799

10. Placental growth factor signaling regulates isoform splicing of vascular endothelial growth factor A in the control of lung cancer cell metastasis.

Authors: Zanfeng Wang; Tingwei Liu
Journal: Mol Cell Biochem Date: 2017-08-31 Impact factor: 3.396

Vascular endothelial growth factor.

1. Evolution of the VEGF-regulated vascular network from a neural guidance system.

Review 2. The mouse retina as an angiogenesis model.

3. Effects of acid-base balance and high or low intensity exercise on VEGF and bFGF.

4. Vascular endothelial growth factor and age-related macular degeneration: from basic science to therapy.

5. Angio-adaptation in unloaded skeletal muscle: new insights into an early and muscle type-specific dynamic process.

6. Changes in biomarkers of inflammation and angiogenesis during androgen deprivation therapy for prostate cancer.

7. Competing endogenous RNA: A novel posttranscriptional regulatory dimension associated with the progression of cancer.

8. Neuroblastoma progression correlates with downregulation of the lymphangiogenesis inhibitor sVEGFR-2.

Review 9. Nanoparticle design strategies for enhanced anticancer therapy by exploiting the tumour microenvironment.

10. Placental growth factor signaling regulates isoform splicing of vascular endothelial growth factor A in the control of lung cancer cell metastasis.