Literature DB >> 19164141

Efficacy of ciprofloxacin in an experimental model of Escherichia coli chorioamnionitis in rabbits.

Elise Launay1, Nicolas Joram, Cédric Jacqueline, Anne Francoise Miegeville, Jocelyne Caillon, Gilles Potel, Jean Christophe Roze, Christèle Gras-Le Guen.   

Abstract

Pregnant rabbits were treated with ciprofloxacin alone or with gentamicin in a model of Escherichia coli chorioamnionitis, and the results were compared with those for untreated rabbits. The survival rate increased and the bacteremia decreased significantly in treated fetuses in comparison to controls (P = 0.003). Nevertheless, rapid selection of resistant mutants is a major limit to ciprofloxacin applications.

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Year:  2009        PMID： 19164141      PMCID： PMC2663122          DOI： 10.1128/AAC.00186-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  17 in total

Review 1.  Inflammation and bronchopulmonary dysplasia.

Authors:  Christian P Speer
Journal:  Semin Neonatol       Date:  2003-02

2.  Intrauterine infection induces programmed cell death in rabbit periventricular white matter.

Authors:  T Debillon; C Gras-Leguen; V Vérielle; N Winer; J Caillon; J C Rozé; P Gressens
Journal:  Pediatr Res       Date:  2000-06       Impact factor: 3.756

3.  Persistent bacteremia in rabbit fetuses despite maternal antibiotic therapy in a novel intrauterine-infection model.

Authors:  C Gras-Le Guen; T Debillon; C Toquet; A Jarry; N Winer; C Jacqueline; M F Kergueris; E Bingen; J C Roze; G Potel; D Bugnon
Journal:  Antimicrob Agents Chemother       Date:  2003-07       Impact factor: 5.191

4.  Management of clinical chorioamnionitis at term.

Authors:  Ronald S Gibbs
Journal:  Am J Obstet Gynecol       Date:  2004-07       Impact factor: 8.661

Review 5.  The relationship between infections and adverse pregnancy outcomes: an overview.

Authors:  R S Gibbs
Journal:  Ann Periodontol       Date:  2001-12

6.  Ciprofloxacin penetration into extravascular spaces in a rabbit model.

Authors:  K L Nichol; L R Peterson; C E Fasching; D N Gerding
Journal:  Antimicrob Agents Chemother       Date:  1984-12       Impact factor: 5.191

7.  Experience with a once-daily dosing program of aminoglycosides in critically ill patients.

Authors:  S E Buijk; J W Mouton; I C Gyssens; H A Verbrugh; H A Bruining
Journal:  Intensive Care Med       Date:  2002-05-30       Impact factor: 17.440

Review 8.  Chorioamnionitis: a risk factor for fetal and neonatal morbidity.

Authors:  Rodolfo Bracci; Giuseppe Buonocore
Journal:  Biol Neonate       Date:  2003

Review 9.  Antibiotic regimens for management of intraamniotic infection.

Authors:  L Hopkins; F Smaill
Journal:  Cochrane Database Syst Rev       Date:  2002

Review 10.  Ciprofloxacin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use.

Authors:  D M Campoli-Richards; J P Monk; A Price; P Benfield; P A Todd; A Ward
Journal:  Drugs       Date:  1988-04       Impact factor: 9.546
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  2 in total

1.  Antibiotic Treatment of Dogs and Cats during Pregnancy.

Authors:  Marcela Rebuelto; María Elena Loza
Journal:  Vet Med Int       Date:  2010-12-14

2.  Detrimental effect of apoptosis of lymphocytes at an early time point of experimental abdominal sepsis.

Authors:  Stefanos Atmatzidis; Ioannis M Koutelidakis; Grigorios Chatzimavroudis; Antigone Kotsaki; Konstantinos Louis; Aikaterini Pistiki; Athina Savva; Anastasia Antonopoulou; Konstantinos Atmatzidis; Evangelos J Giamarellos-Bourboulis
Journal:  BMC Infect Dis       Date:  2011-11-20       Impact factor: 3.090
  2 in total

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