STUDY OBJECTIVE: To investigate whether diabetes, hypertension (HTN), and obesity can be considered risk factors for endometrial polyps (EPs) independently of age and menopausal status. DESIGN: Retrospective analysis (Canadian Task Force classification III). SETTING: Department of Obstetrics and Gynecology of the University of Foggia, Italy. PATIENTS: A total of 353 Caucasian women undergoing office hysteroscopy to assess abnormal uterine bleeding, infertility, cervical polyps, and abnormal sonographic patterns. INTERVENTIONS: Demographic characteristics and data on diabetes, HTN, and menopausal status were collected and anthropometric parameters were analyzed. Vaginoscopic hysteroscopy was performed with a 5-mm continuous-flow operative office hysteroscope. When present, EPs were treated during the same procedure by means of 5-Fr scissors or electrode. MEASUREMENTS AND MAIN RESULTS: In 134 (38%) of 353 cases, EPs were found. Univariable and multivariable analysis were performed to verify the presence of a statistically significant association among age, menopause, HTN, obesity, diabetes (independent variables), and the presence of EPs. Univariable logistic analysis showed a statistically significant association among age, menopause, HTN, obesity, and the presence of EPs. However, when multivariable logistic regression was performed, all the independent variables, except age, lost statistical significance (OR 1.05, 95% CI 1.02-1.07, p <.001). CONCLUSION: Although it appears that EP is a disorder of aging, the significance of diabetes, HTN, and obesity, as well as menopause, on the development of EPs should be reconsidered.
STUDY OBJECTIVE: To investigate whether diabetes, hypertension (HTN), and obesity can be considered risk factors for endometrial polyps (EPs) independently of age and menopausal status. DESIGN: Retrospective analysis (Canadian Task Force classification III). SETTING: Department of Obstetrics and Gynecology of the University of Foggia, Italy. PATIENTS: A total of 353 Caucasian women undergoing office hysteroscopy to assess abnormal uterine bleeding, infertility, cervical polyps, and abnormal sonographic patterns. INTERVENTIONS: Demographic characteristics and data on diabetes, HTN, and menopausal status were collected and anthropometric parameters were analyzed. Vaginoscopic hysteroscopy was performed with a 5-mm continuous-flow operative office hysteroscope. When present, EPs were treated during the same procedure by means of 5-Fr scissors or electrode. MEASUREMENTS AND MAIN RESULTS: In 134 (38%) of 353 cases, EPs were found. Univariable and multivariable analysis were performed to verify the presence of a statistically significant association among age, menopause, HTN, obesity, diabetes (independent variables), and the presence of EPs. Univariable logistic analysis showed a statistically significant association among age, menopause, HTN, obesity, and the presence of EPs. However, when multivariable logistic regression was performed, all the independent variables, except age, lost statistical significance (OR 1.05, 95% CI 1.02-1.07, p <.001). CONCLUSION: Although it appears that EP is a disorder of aging, the significance of diabetes, HTN, and obesity, as well as menopause, on the development of EPs should be reconsidered.
Authors: Carlo Saccardi; Salvatore Gizzo; Kathrin Ludwig; Maria Guido; Mara Scarton; Michele Gangemi; Raffaele Tinelli; Pietro Salvatore Litta Journal: Biomed Res Int Date: 2013-08-22 Impact factor: 3.411
Authors: Marco Antonio Lenci; Vanessa Alessandra Lui do Nascimento; Ana Beatriz Grandini; Walid Makin Fahmy; Daniella de Batista Depes; Fausto Farah Baracat; Reginaldo Guedes Coelho Lopes Journal: Einstein (Sao Paulo) Date: 2014 Jan-Mar
Authors: Wedad Al-Madani; Anwar E Ahmed; Haitham Arabi; Sumaiah Al Khodairy; Nashmia Al Mutairi; Abdul Rahman Jazieh Journal: Saudi Med J Date: 2019-05 Impact factor: 1.484