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Literature DB >> 19161732

A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery.

Russell W J Millner¹, Alan S Lockhart, Helen Bird, Christos Alexiou.

Abstract

Celox (MedTrade Products Ltd, Cheshire, UK) is a proprietary preparation of chitosan, indicated for moderate to severe hemorrhage and currently used for hemostasis in the emergency and military settings. We describe its lifesaving use in 2 patients undergoing cardiothoracic surgery in which conventional techniques had failed.

Entities: Chemical Disease Species

Mesh：

Substances：
Hemostatics
Chitosan

Year: 2009 PMID： 19161732 DOI： 10.1016/j.athoracsur.2008.09.046

Source DB: PubMed Journal: Ann Thorac Surg ISSN： 0003-4975 Impact factor: 4.330

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Cited

14 in total

1. Successful use of a military haemostatic agent in patients undergoing extracorporeal circulatory assistance and delayed sternal closure.

Authors: Luigi Muzzi; Giulio Tommasino; Enrico Tucci; Eugenio Neri
Journal: Interact Cardiovasc Thorac Surg Date: 2012-02-24

2. eComment. Activated recombinant factor VII in intractable bleeding after cardiac surgery.

Authors: Jamil Hajj-Chahine
Journal: Interact Cardiovasc Thorac Surg Date: 2012-06

Review 3. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects.

Authors: Tianhong Dai; Masamitsu Tanaka; Ying-Ying Huang; Michael R Hamblin
Journal: Expert Rev Anti Infect Ther Date: 2011-07 Impact factor: 5.091

Review 4. Hemostasis and nanotechnology.

Authors: Patrick Hangge; Jonathan Stone; Hassan Albadawi; Yu Shrike Zhang; Ali Khademhosseini; Rahmi Oklu
Journal: Cardiovasc Diagn Ther Date: 2017-12

5. Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

Authors: Lingegowda S Mangala; Hongyu Wang; Dahai Jiang; Sherry Y Wu; Anoma Somasunderam; David E Volk; Ganesh L R Lokesh; Xin Li; Sunila Pradeep; Xianbin Yang; Monika Haemmerle; Cristian Rodriguez-Aguayo; Archana S Nagaraja; Rajesha Rupaimoole; Emine Bayraktar; Recep Bayraktar; Li Li; Takemi Tanaka; Wei Hu; Cristina Ivan; Kshipra M Gharpure; Michael H McGuire; Varatharasa Thiviyanathan; Xinna Zhang; Sourindra N Maiti; Nataliya Bulayeva; Hyun-Jin Choi; Piotr L Dorniak; Laurence Jn Cooper; Kevin P Rosenblatt; Gabriel Lopez-Berestein; David G Gorenstein; Anil K Sood
Journal: JCI Insight Date: 2016-10-20

A new hemostatic agent: initial life-saving experience with Celox (chitosan) in cardiothoracic surgery.

1. Successful use of a military haemostatic agent in patients undergoing extracorporeal circulatory assistance and delayed sternal closure.

2. eComment. Activated recombinant factor VII in intractable bleeding after cardiac surgery.

Review 3. Chitosan preparations for wounds and burns: antimicrobial and wound-healing effects.

Review 4. Hemostasis and nanotechnology.

5. Improving vascular maturation using noncoding RNAs increases antitumor effect of chemotherapy.

Review 6. Biomaterials and Advanced Technologies for Hemostatic Management of Bleeding.

7. Electrospun Chitosan-based Fibers for Wound Healing Applications.

8. Celox-coated gauze for the treatment of civilian penetrating trauma: a randomized clinical trial.

9. Efficacy of Chitosan in promoting wound healing in extraction socket: A prospective study.

Review 10. Overview of Agents Used for Emergency Hemostasis.