Literature DB >> 19160085

Genomic location of the bovine growth hormone secretagogue receptor (GHSR) gene and investigation of genetic polymorphism.

F G Colinet1, S Vanderick, B Charloteaux, A Eggen, N Gengler, B Renaville, R Brasseur, D Portetelle, Robert Renaville.   

Abstract

The growth hormone secretagogue receptor (GHSR) is involved in the regulation of energetic homeostasis and GH secretion. In this study, the bovine GHSR gene was mapped to BTA1 between BL26 and BMS4004. Two different bovine GHSR CDS (GHSR1a and GHSR1b) were sequenced. Six polymorphisms (five SNPs and one 3-bp indel) were also identified, three of them leading to amino acid variations L24V, D194N, and Del R242. These variations are located in the extracellular N-terminal end, the exoloop 2, and the cytoloop 3 of the receptor, respectively.

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Year:  2009        PMID: 19160085     DOI: 10.1080/10495390802602926

Source DB:  PubMed          Journal:  Anim Biotechnol        ISSN: 1049-5398            Impact factor:   2.282


  2 in total

1.  Genome-wide detection of selective signatures in Simmental cattle.

Authors:  Huizhong Fan; Yang Wu; Xin Qi; Jingjing Zhang; Juan Li; Xue Gao; Lupei Zhang; Junya Li; HuiJiang Gao
Journal:  J Appl Genet       Date:  2014-03-12       Impact factor: 3.240

Review 2.  Ghrelin: ghrelin as a regulatory Peptide in growth hormone secretion.

Authors:  Nazli Khatib; Shilpa Gaidhane; Abhay M Gaidhane; Mahanaaz Khatib; Padam Simkhada; Dilip Gode; Quazi Syed Zahiruddin
Journal:  J Clin Diagn Res       Date:  2014-08-20
  2 in total

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