| Literature DB >> 19159802 |
Hao Yue1, Zifeng Pi, Fengrui Song, Zhiqiang Liu, Zongwei Cai, Shuying Liu.
Abstract
Studies of aconitine-type alkaloids in the Chinese herb Aconitum Carmichaeli were performed by HPLC/ESIMS/MS(n) and FTICR/ESIMS in positive ion mode. The characteristic fragmentation pathways in the MS(n) spectra were summarized based on previously published research literature and further study. According to the fragmentation pathways of mass spectrometry, results from the analysis of standard compounds and reports from literature, 111 compounds were identified or deduced in a total of 117 found compounds in A. Carmichaeli. In the 11 monoester-diterpenoid alkaloids (MDA), 10 diesterditerpenoid alkaloids (DDA) and 81 lipo-alkaloids, the novel alkaloids including 1 MDA, 2 DDA and 48 lipo-alkaloids were detected. In addition, 1 DDA, 7 lipo-alkaloids and 2 alkaloids with small molecular weights that possess C19-norditerpenoid skeleton were reported in A. Carmichaeli for the first time.Entities:
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Year: 2008 PMID： 19159802 DOI： 10.1016/j.talanta.2008.10.022
Source DB: PubMed Journal: Talanta ISSN： 0039-9140 Impact factor: 6.057