Literature DB >> 19156419

Massive lower gastrointestinal haemorrhage, successfully treated with corticosteroids, as main symptom of Schönlein-Henoch purpura.

F Alvarez-Caro1, J A Concha-Torre, I García-Hernández, S Menéndez-Cuervo, M Los Arcos-Solas, J Santos-Juanes, E Ramos-Polo.   

Abstract

Schönlein-Henoch purpura is a small vessel disease that affects mainly skin and kidney, although several gastrointestinal symptoms may occur including abdominal pain, intussusception, perforation or bleeding. Massive lower gastrointestinal haemorrhage is rare and even more as the main symptom of the disease. We present a case of a 2-year-old boy with Schönlein-Henoch purpura who developed a massive lower gastrointestinal bleeding requiring blood transfusion. In this patient both Schönlein-Henoch purpura and gastrointestinal haemorrhage were successfully treated with intravenous methylprednisolone, avoiding surgical intervention. Physicians need to have a high index of suspicion when evaluating these patients, even more when dermatologic signs are scarce. Glucocorticosteroid therapy may be effective when treating severe gastrointestinal symptoms.

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Year:  2009        PMID: 19156419     DOI: 10.1007/s00296-009-0853-3

Source DB:  PubMed          Journal:  Rheumatol Int        ISSN: 0172-8172            Impact factor:   2.631


  22 in total

Review 1.  Intravenous immunoglobulin therapy for severe digestive manifestations of Henoch-Schönlein purpura.

Authors:  T Lamireau; L Rebouissoux; J P Hehunstre
Journal:  Acta Paediatr       Date:  2001-09       Impact factor: 2.299

2.  Henoch-Schönlein purpura in children from northwestern Spain: a 20-year epidemiologic and clinical study.

Authors:  M C Calviño; J Llorca; C García-Porrúa; J L Fernández-Iglesias; P Rodriguez-Ledo; M A González-Gay
Journal:  Medicine (Baltimore)       Date:  2001-09       Impact factor: 1.889

3.  The American College of Rheumatology 1990 criteria for the classification of hypersensitivity vasculitis.

Authors:  L H Calabrese; B A Michel; D A Bloch; W P Arend; S M Edworthy; A S Fauci; J F Fries; G G Hunder; R Y Leavitt; J T Lie
Journal:  Arthritis Rheum       Date:  1990-08

Review 4.  Atypical clinical course of Henoch-Schonlein purpura.

Authors:  David Lawee
Journal:  Can Fam Physician       Date:  2008-08       Impact factor: 3.275

Review 5.  Henoch-Schönlein purpura in children. Report of 100 patients and review of the literature.

Authors:  F T Saulsbury
Journal:  Medicine (Baltimore)       Date:  1999-11       Impact factor: 1.889

6.  Henoch-Schönlein purpura in adulthood and childhood: two different expressions of the same syndrome.

Authors:  R Blanco; V M Martínez-Taboada; V Rodríguez-Valverde; M García-Fuentes; M A González-Gay
Journal:  Arthritis Rheum       Date:  1997-05

7.  A nationwide survey on epidemiological characteristics of childhood Henoch-Schönlein purpura in Taiwan.

Authors:  Y-H Yang; C-F Hung; C-R Hsu; L-C Wang; Y-H Chuang; Y-T Lin; B-L Chiang
Journal:  Rheumatology (Oxford)       Date:  2005-01-25       Impact factor: 7.580

8.  Gastrointestinal manifestations in Henoch-Schönlein purpura: a review of 261 patients.

Authors:  W-L Chang; Y-H Yang; Y-T Lin; B-L Chiang
Journal:  Acta Paediatr       Date:  2004-11       Impact factor: 2.299

9.  Successful treatment of mesenteric vasculitis caused by Henoch-Schönlein purpura with methylprednisolone pulse therapy.

Authors:  L Wang; F-C Huang; S-F Ko; M-T Cheng
Journal:  Clin Rheumatol       Date:  2003-05       Impact factor: 2.980

10.  Henoch-Schönlein purpura nephritis: course of disease and efficacy of cyclophosphamide.

Authors:  Penina Tarshish; Jay Bernstein; Chester M Edelmann
Journal:  Pediatr Nephrol       Date:  2003-11-22       Impact factor: 3.714

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  1 in total

1.  Acute Esophageal Necrosis Presenting With Henoch-Schönlein Purpura.

Authors:  Natalya Iorio; Gregory R Bernstein; Zubair Malik; Ron Schey
Journal:  ACG Case Rep J       Date:  2015-10-09
  1 in total

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