Literature DB >> 15513566

Gastrointestinal manifestations in Henoch-Schönlein purpura: a review of 261 patients.

W-L Chang1, Y-H Yang, Y-T Lin, B-L Chiang.   

Abstract

AIM: Henoch-Schönlein purpura is an IgA-mediated autoimmune vasculitis of children. It often presents with symptoms including purpuric rash, abdominal pain, renal involvement or arthritis. Abdominal pain is a frequent symptom in children with HSP and raises the suspicion of intussusception or perforation. We sought to evaluate abdominal pain via stool occult blood and image studies.
METHODS: A retrospective study of 261 patients diagnosed with Henoch-Schönlein purpura from December 1991 to December 2001 was conducted. Image studies, including abdominal echo, abdominal CT and panendoscopy, were performed for patients who suffered from abdominal pain.
RESULTS: Of the 261 patients, 151 (58%) had abdominal pain, and 46 (17.6%) suffered either overt gastrointestinal bleeding or had positive stool occult blood. Seven patients had gross bloody stools. One acute intussusception and one bowel perforation were noted. One patient suffered from hypovolemic shock due to massive gastrointestinal bleeding. When stool occult blood was 3+ or 4+, the incidence of a positive image finding was high.
CONCLUSION: We found that stool occult blood and image studies may be necessary regarding severe gastrointestinal involvement. Ultrasonography is an important tool when intussusception or bowel perforation is suspected. Monitoring the vital signs is important, especially in patients with massive gastrointestinal bleeding.

Entities:  

Mesh:

Year:  2004        PMID: 15513566     DOI: 10.1080/08035250410020181

Source DB:  PubMed          Journal:  Acta Paediatr        ISSN: 0803-5253            Impact factor:   2.299


  21 in total

Review 1.  Ultrasound assessment of the bowel: inflammatory bowel disease and conditions beyond.

Authors:  Michael L Francavilla; Sudha A Anupindi; Summer L Kaplan; David M Biko
Journal:  Pediatr Radiol       Date:  2017-08-04

2.  Henoch-Schönlein purpura: a clinical case with dramatic presentation.

Authors:  João Bento; Adriana Magalhães; Conceição Souto Moura; Venceslau Hespanhol
Journal:  BMJ Case Rep       Date:  2010-09-09

3.  Ultrasound in the evaluation of necrotic bowel in children: A pictorial essay.

Authors:  Mark Qw Wang; Margaret Yw Lee; Harvey El Teo
Journal:  Ultrasound       Date:  2018-12-03

Review 4.  Gastrointestinal manifestations of Henoch-Schonlein Purpura.

Authors:  Ellen C Ebert
Journal:  Dig Dis Sci       Date:  2008-03-20       Impact factor: 3.199

5.  Henoch-Schönlein purpura in children: limited benefit of corticosteroids.

Authors:  Joel Bluman; Ran D Goldman
Journal:  Can Fam Physician       Date:  2014-11       Impact factor: 3.275

Review 6.  [Skin diseases due to systemic vasculitides and vasculopathies].

Authors:  S Volc; J C Maier; M Röcken
Journal:  Hautarzt       Date:  2016-12       Impact factor: 0.751

7.  Gastrointestinal manifestations in systemic autoimmune diseases.

Authors:  M Cojocaru; Inimioara Mihaela Cojocaru; Isabela Silosi; Camelia Doina Vrabie
Journal:  Maedica (Buchar)       Date:  2011-01

Review 8.  Clinical practice: Diagnosis and management of Henoch-Schönlein purpura.

Authors:  Hugh J McCarthy; E Jane Tizard
Journal:  Eur J Pediatr       Date:  2009-12-12       Impact factor: 3.183

9.  Gastrointestinal involvement in IgA vasculitis: a single-center 11-year study on a cohort of 118 children.

Authors:  Chiara Rubino; Costanza Monacelli; Edoardo Marrani; Monica Paci; Giuseppe Indolfi; Gabriele Simonini; Sandra Trapani
Journal:  Clin Rheumatol       Date:  2021-07-17       Impact factor: 2.980

10.  Henoch-Schönlein pupura complicated by perforation of the gallbladder.

Authors:  Atsushi Hashimoto; Reiko Matsushita; Nobuko Iizuka; Miho Kimura; Toshimichi Matsui; Sumiaki Tanaka; Akira Ishikawa; Hirahito Endo; Shunsei Hirohata
Journal:  Rheumatol Int       Date:  2008-10-03       Impact factor: 2.631

View more

北京卡尤迪生物科技股份有限公司 © 2022-2023.