BACKGROUND/AIMS: This study was conducted to evaluate the clinical features and treatment outcome of gastric cancer associated with pregnancy. METHODS: Clinicopathologic characteristics of 15 patients who were diagnosed as having gastric cancer during pregnancy or within 1 year after delivery (the P-related group) were compared with those of 53 age-matched pregnancy-unrelated gastric cancer patients (the control group). RESULTS: Significant differences were found in tumor stage and surgical curability; the numbers of stage IV disease were 12 (80%) and 21 (40%; p = 0.006), and those of curative resection were 4 (27%) and 20 (62%; p = 0.02) in the P-related and the control group, respectively. Three-year survival rate was significantly lower in the P-related group (23.3%) than in the control group (52.8%; p = 0.007). In the P-related group, only 3 patients, including one patient diagnosed using endoscopy, survived without recurrences. In the multivariate analysis, pregnancy was not identified as an independent risk factor associated with poor outcome. CONCLUSION: Gastric cancer associated with pregnancy is discovered at its advanced stage and consequently shows a dismal prognosis. Considering that the patients who underwent curative resection have a favorable prognosis, primary efforts should be focused on early diagnosis. Copyright (c) 2009 S. Karger AG, Basel.
BACKGROUND/AIMS: This study was conducted to evaluate the clinical features and treatment outcome of gastric cancer associated with pregnancy. METHODS: Clinicopathologic characteristics of 15 patients who were diagnosed as having gastric cancer during pregnancy or within 1 year after delivery (the P-related group) were compared with those of 53 age-matched pregnancy-unrelated gastric cancerpatients (the control group). RESULTS: Significant differences were found in tumor stage and surgical curability; the numbers of stage IV disease were 12 (80%) and 21 (40%; p = 0.006), and those of curative resection were 4 (27%) and 20 (62%; p = 0.02) in the P-related and the control group, respectively. Three-year survival rate was significantly lower in the P-related group (23.3%) than in the control group (52.8%; p = 0.007). In the P-related group, only 3 patients, including one patient diagnosed using endoscopy, survived without recurrences. In the multivariate analysis, pregnancy was not identified as an independent risk factor associated with poor outcome. CONCLUSION:Gastric cancer associated with pregnancy is discovered at its advanced stage and consequently shows a dismal prognosis. Considering that the patients who underwent curative resection have a favorable prognosis, primary efforts should be focused on early diagnosis. Copyright (c) 2009 S. Karger AG, Basel.
Authors: Min Jeong Song; Young Soo Park; Ho June Song; Se Jeong Park; Ji Yong Ahn; Kee Don Choi; Gin Hyug Lee; Hwoon-Yong Jung; Jeong Hwan Yook; Byung Sik Kim Journal: Gut Liver Date: 2016-09-15 Impact factor: 4.519
Authors: Charlotte Maggen; Christianne A Lok; Elyce Cardonick; Mathilde van Gerwen; Petronella B Ottevanger; Ingrid A Boere; Martin Koskas; Michael J Halaska; Robert Fruscio; Mina M Gziri; Petronella O Witteveen; Kristel Van Calsteren; Frédéric Amant Journal: Acta Obstet Gynecol Scand Date: 2019-10-16 Impact factor: 3.636