Warning: Undefined array key "mm" in /www/wwwroot/www.ai-bt.com/si.php on line 10 Deprecated: trim(): Passing null to parameter #1 ($string) of type string is deprecated in /www/wwwroot/www.ai-bt.com/si.php on line 10 Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle.

Literature DB >> 19148773

Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle.

Bao Zhang¹, Hong Chen, Yikun Guo, Liangzhi Zhang, Miao Zhao, Xianyong Lan, Chunlei Zhang, Chuanying Pan, Shenrong Hu, Juqiang Wang, Chuzhao Lei.

Abstract

GH secretagogue receptor (ghrelin receptor, GHSR) is known to be involved in the control of GH release by mediating the strong stimulatory effect of the endogenous ligand, ghrelin, on GH secretion. Associations between the GHSR gene polymorphism and the growth traits were revealed in Nanyang cattle. The mutations at nt456(G > A) and nt667(C > T) were complete linkage and located in exon 1 of the coding region of the GHSR gene. Least squares analysis revealed a significant statistical effect (P < 0.05) of the GHSR gene different genotypes on body weight and average daily gain at 6 months of age in Nanyang cattle. Individuals with GHSR-MM genotype showed higher body weight and average daily gain than individuals with GHSR-MN genotype.

Entities: Gene Species

Mesh：

Substances：
Receptors, Ghrelin

Year: 2009 PMID： 19148773 DOI： 10.1007/s11033-008-9442-x

Source DB: PubMed Journal: Mol Biol Rep ISSN： 0301-4851 Impact factor: 2.316

20 in total

Review 1. Ghrelin: the link connecting growth with metabolism and energy homeostasis.

Authors: Felipe F Casanueva; Carlos Dieguez
Journal: Rev Endocr Metab Disord Date: 2002-12 Impact factor: 6.514

Review 2. Development of growth hormone secretagogues.

Authors: Roy G Smith
Journal: Endocr Rev Date: 2005-04-06 Impact factor: 19.871

3. Association of the Ghrelin receptor gene region with left ventricular hypertrophy in the general population: results of the MONICA/KORA Augsburg Echocardiographic Substudy.

Authors: Andrea Baessler; Anne E Kwitek; Marcus Fischer; Martina Koehler; Wibke Reinhard; Jeanette Erdmann; Guenter Riegger; Angela Doering; Heribert Schunkert; Christian Hengstenberg
Journal: Hypertension Date: 2006-03-27 Impact factor: 10.190

4. Ghrelin induces adiposity in rodents.

Authors: M Tschöp; D L Smiley; M L Heiman
Journal: Nature Date: 2000-10-19 Impact factor: 49.962

5. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

Authors: David E Cummings; David S Weigle; R Scott Frayo; Patricia A Breen; Marina K Ma; E Patchen Dellinger; Jonathan Q Purnell
Journal: N Engl J Med Date: 2002-05-23 Impact factor: 91.245

6. Circulating ghrelin levels are decreased in human obesity.

Authors: M Tschöp; C Weyer; P A Tataranni; V Devanarayan; E Ravussin; M L Heiman
Journal: Diabetes Date: 2001-04 Impact factor: 9.461

7. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.

Authors: F Broglio; E Arvat; A Benso; C Gottero; G Muccioli; M Papotti; A J van der Lely; R Deghenghi; E Ghigo
Journal: J Clin Endocrinol Metab Date: 2001-10 Impact factor: 5.958

8. Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.

Authors: Jacques Pantel; Marie Legendre; Sylvie Cabrol; Latifa Hilal; Yassir Hajaji; Séverine Morisset; Sylvie Nivot; Marie-Pierre Vie-Luton; Dominique Grouselle; Marc de Kerdanet; Abdelkrim Kadiri; Jacques Epelbaum; Yves Le Bouc; Serge Amselem
Journal: J Clin Invest Date: 2006-03 Impact factor: 14.808

9. A receptor in pituitary and hypothalamus that functions in growth hormone release.

Authors: A D Howard; S D Feighner; D F Cully; J P Arena; P A Liberator; C I Rosenblum; M Hamelin; D L Hreniuk; O C Palyha; J Anderson; P S Paress; C Diaz; M Chou; K K Liu; K K McKee; S S Pong; L Y Chaung; A Elbrecht; M Dashkevicz; R Heavens; M Rigby; D J Sirinathsinghji; D C Dean; D G Melillo; A A Patchett; R Nargund; P R Griffin; J A DeMartino; S K Gupta; J M Schaeffer; R G Smith; L H Van der Ploeg
Journal: Science Date: 1996-08-16 Impact factor: 47.728

10. Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature.

Authors: Hai-Jun Wang; Frank Geller; Astrid Dempfle; Nadine Schäuble; Susann Friedel; Peter Lichtner; Francisco Fontenla-Horro; Stefan Wudy; Sandra Hagemann; Ludwig Gortner; Klaus Huse; Helmut Remschmidt; Thomas Bettecken; Thomas Meitinger; Helmut Schäfer; Johannes Hebebrand; Anke Hinney
Journal: J Clin Endocrinol Metab Date: 2004-01 Impact factor: 5.958

8 in total

Associations of polymorphism within the GHSR gene with growth traits in Nanyang cattle.

Review 1. Ghrelin: the link connecting growth with metabolism and energy homeostasis.

Review 2. Development of growth hormone secretagogues.

3. Association of the Ghrelin receptor gene region with left ventricular hypertrophy in the general population: results of the MONICA/KORA Augsburg Echocardiographic Substudy.

4. Ghrelin induces adiposity in rodents.

5. Plasma ghrelin levels after diet-induced weight loss or gastric bypass surgery.

6. Circulating ghrelin levels are decreased in human obesity.

7. Ghrelin, a natural GH secretagogue produced by the stomach, induces hyperglycemia and reduces insulin secretion in humans.

8. Loss of constitutive activity of the growth hormone secretagogue receptor in familial short stature.

9. A receptor in pituitary and hypothalamus that functions in growth hormone release.

10. Ghrelin receptor gene: identification of several sequence variants in extremely obese children and adolescents, healthy normal-weight and underweight students, and children with short normal stature.

1. One novel SNP of growth hormone gene and its associations with growth and carcass traits in ducks.

2. Polymorphism of DLK1 and CLPG gene and their association with phenotypic traits in Chinese cattle.

3. Associations of polymorphisms in GHRL, GHSR, and IGF1R genes with feed efficiency in chickens.

4. Molecular characterization, expression pattern, polymorphism and association analysis of bovine ADAMTSL3 gene.

5. Study on polymerization effect of polyembryony genes by SSCP marker and family trees in Chinese goats.

6. The polymorphisms of bovine VEGF gene and their associations with growth traits in Chinese cattle.

7. Novel polymorphisms of goat growth hormone and growth hormone receptor genes and their effects on growth traits.

8. Associations of GHSR gene polymorphisms with chicken growth and carcass traits.