OBJECTIVE: To determine in a systematic review, whether interventions for infant development that involve parents, improve neurodevelopment at 12 months corrected age or older. STUDY DESIGN: Randomized trials were identified where an infant intervention was aimed to improve development and involved parents of preterms; and long-term neurodevelopment using standardized tests at 12 months (or longer) was reported. RESULT: Identified studies (n=25) used a variety of interventions including parent education, infant stimulation, home visits or individualized developmental care. Meta-analysis at 12 months (N=2198 infants) found significantly higher mental (N=2198) and physical (N=1319) performance scores favoring the intervention group. At 24 months, the mental (N=1490) performance scores were improved, but physical (N=1025) performance scores were not statistically significant. The improvement in neurodevelopmental outcome was not sustained at 36 months (N=961) and 5 years (N=1017). CONCLUSION: Positive clinically meaningful effects (>5 points) are seen to an age of 36 months, but are no longer present at 5 years.
OBJECTIVE: To determine in a systematic review, whether interventions for infant development that involve parents, improve neurodevelopment at 12 months corrected age or older. STUDY DESIGN: Randomized trials were identified where an infant intervention was aimed to improve development and involved parents of preterms; and long-term neurodevelopment using standardized tests at 12 months (or longer) was reported. RESULT: Identified studies (n=25) used a variety of interventions including parent education, infant stimulation, home visits or individualized developmental care. Meta-analysis at 12 months (N=2198 infants) found significantly higher mental (N=2198) and physical (N=1319) performance scores favoring the intervention group. At 24 months, the mental (N=1490) performance scores were improved, but physical (N=1025) performance scores were not statistically significant. The improvement in neurodevelopmental outcome was not sustained at 36 months (N=961) and 5 years (N=1017). CONCLUSION: Positive clinically meaningful effects (>5 points) are seen to an age of 36 months, but are no longer present at 5 years.
Authors: Sonia Khurana; Audrey E Kane; Shaaron E Brown; Talicia Tarver; Stacey C Dusing Journal: Dev Med Child Neurol Date: 2020-02-19 Impact factor: 5.449
Authors: Sarah Mccue Horwitz; Ann Leibovitz; Emily Lilo; Booil Jo; Anne Debattista; Nick St John; Richard J Shaw Journal: Infant Ment Health J Date: 2014-12-01
Authors: Amy J Lisanti; Aparna Kumar; Ryan Quinn; Jesse L Chittams; Barbara Medoff-Cooper; Abigail C Demianczyk Journal: Cardiol Young Date: 2021-04-05 Impact factor: 1.093
Authors: Anneke Tooten; Hannah N Hoffenkamp; Ruby A S Hall; Frans Willem Winkel; Marij Eliëns; Ad J J M Vingerhoets; Hedwig J A van Bakel Journal: BMC Pediatr Date: 2012-06-18 Impact factor: 2.125