Literature DB >> 19145322

Cardioprotective effects of trimetazidine and a combination of succinic and malic acids in acute myocardial ischemia.

V A Khazanov1, A A Kiseliova, K Yu Vasiliev, G A Chernyschova.   

Abstract

A mixture of mitochondrial substrates of succinic and malic acids more effectively than antihypoxant trimetazidine prevented functional and metabolic disorders in rat myocardium during acute ischemia: reduces T wave amplitude, QT interval, number and duration of arrhythmias, and restores oxidation-phosphorylation coupling.

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Year:  2008        PMID： 19145322     DOI： 10.1007/s10517-008-0259-3

Source DB:  PubMed          Journal:  Bull Exp Biol Med        ISSN： 0007-4888            Impact factor:   0.804


  4 in total

Review 1.  Emerging concepts in liver graft preservation.

Authors:  Mohamed Bejaoui; Eirini Pantazi; Emma Folch-Puy; Pedro M Baptista; Agustín García-Gil; René Adam; Joan Roselló-Catafau
Journal:  World J Gastroenterol       Date:  2015-01-14       Impact factor: 5.742

2.  Investigation of the protective mechanism of leonurine against acute myocardial ischemia by an integrated metabolomics and network pharmacology strategy.

Authors:  Weiwei Rong; Jiejia Li; Lifeng Wang; Shanshan Luo; Tulu Liang; Xunjia Qian; Xiaodan Zhang; Qinbei Zhou; Yizhun Zhu; Qing Zhu
Journal:  Front Cardiovasc Med       Date:  2022-08-22

3.  Metabonomic strategy to the evaluation of chinese medicine compound danshen dripping pills interfering myocardial ischemia in rats.

Authors:  Xue Xin; Haimiao Zou; Ningning Zheng; Xinchun Xu; Yinmin Liu; Xiaoxian Wang; Hongbing Wu; Lina Lu; Jing Su; Mingfeng Qiu; Xiaoyan Wang
Journal:  Evid Based Complement Alternat Med       Date:  2013-05-02       Impact factor: 2.629

4.  Effects of trimetazidine on mitochondrial respiratory function, biosynthesis, and fission/fusion in rats with acute myocardial ischemia.

Authors:  Wen Shi; Wenfeng Shangguan; Yue Zhang; Can Li; Guangping Li
Journal:  Anatol J Cardiol       Date:  2017-07-25       Impact factor: 1.596
  4 in total

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