Literature DB >> 19143886

Use of fresh-frozen plasma at Royal Darwin Hospital: a retrospective audit.

S Moylan1, F Szabo, H Scott, G Kwok.   

Abstract

BACKGROUND: The aim of the study was to assess the appropriateness of use of fresh-frozen plasma (FFP) at Royal Darwin Hospital against the National Health and Medical Research Council and Australian and New Zealand Society for Blood Transfusion guidelines.
METHODS: A retrospective review of blood product request forms, online pathology storage system data, pathology records and clinical notes between 1 January 2006 and 31 December 2006 was carried out. The appropriateness of requests was assessed against existing guidelines. The percentage of appropriate and inappropriate FFP transfusions was obtained.
RESULTS: Six hundred and forty-eight of 950 units (68%) of FFP were used with an appropriate indication as per National Health and Medical Research Council/Australian and New Zealand Society for Blood Transfusion guidelines. Of the remaining units, 14% (137 units) was given without a clear indication and a decision of appropriateness could not be established for 17% (165 units) because of inadequate clinical or pathology information (e.g. coagulation results). Multiple issues around prescribing practice were identified.
CONCLUSION: There is significant use of FFP at Royal Darwin Hospital without clear clinical indication. The employment of a transfusion nurse to monitor use of FFP (and other blood products) and provide education is aimed at improving transfusion efficiency and patient safety.

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Year:  2008        PMID: 19143886     DOI: 10.1111/j.1445-5994.2008.01730.x

Source DB:  PubMed          Journal:  Intern Med J        ISSN: 1444-0903            Impact factor:   2.048


  6 in total

Review 1.  Evaluation of clinical appropriateness of blood transfusion.

Authors:  Franco Verlicchi
Journal:  Blood Transfus       Date:  2010-04       Impact factor: 3.443

2.  Red cell transfusion in orthopaedic surgery: a benchmark study performed combining data from different data sources.

Authors:  Franco Verlicchi; Fausto Desalvo; Gabriele Zanotti; Loretta Morotti; Ivana Tomasini
Journal:  Blood Transfus       Date:  2011-04-12       Impact factor: 3.443

3.  Prophylactic plasma transfusion for patients undergoing non-cardiac surgery.

Authors:  Jonathan Huber; Simon J Stanworth; Carolyn Doree; Marialena Trivella; Susan J Brunskill; Sally Hopewell; Kirstin L Wilkinson; Lise J Estcourt
Journal:  Cochrane Database Syst Rev       Date:  2017-08-17

4.  Prophylactic plasma transfusion for patients without inherited bleeding disorders or anticoagulant use undergoing non-cardiac surgery or invasive procedures.

Authors:  Jonathan Huber; Simon J Stanworth; Carolyn Doree; Patricia M Fortin; Marialena Trivella; Susan J Brunskill; Sally Hopewell; Kirstin L Wilkinson; Lise J Estcourt
Journal:  Cochrane Database Syst Rev       Date:  2019-11-28

5.  The evaluation of the audit of Fresh-Frozen Plasma (FFP) usage in emergency department.

Authors:  Emine Emektar; Seda Dagar; Seref Kerem Corbacioglu; Huseyin Uzunosmanoglu; Mehmet Veysel Oncul; Yunsur Cevik
Journal:  Turk J Emerg Med       Date:  2016-08-20

6.  Long-term audit of the use of fresh frozen plasma in a university hospital.

Authors:  Abdel Galil M Abdel Gader; Abeer K Al-Ghumlas; Abdul Kareem M Al Momen; Sitel Banat A Awadalla; Motasim Badri
Journal:  J Taibah Univ Med Sci       Date:  2017-06-09
  6 in total

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