Literature DB >> 19143624

ESCRTs and human disease.

Suraj Saksena1, Scott D Emr.   

Abstract

The ESCRT (endosomal sorting complex required for transport) machinery plays a critical role in receptor down-regulation, retroviral budding, and other normal and pathological processes. The ESCRT components are conserved in all five major subgroups of eukaryotes. This review summarizes the growing number of links identified between ESCRT-mediated protein sorting in the MVB (multivesicular body) pathway and various human diseases.

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Year:  2009        PMID： 19143624     DOI： 10.1042/BST0370167

Source DB:  PubMed          Journal:  Biochem Soc Trans        ISSN： 0300-5127            Impact factor:   5.407


  53 in total

Review 1.  Microautophagy: lesser-known self-eating.

Authors:  Wen-wen Li; Jian Li; Jin-ku Bao
Journal:  Cell Mol Life Sci       Date:  2011-11-12       Impact factor: 9.261

2.  Viral infection: Moving through complex and dynamic cell-membrane structures.

Authors:  Jonathan Barroso-González; Laura García-Expósito; Julià Blanco; Agustín Valenzuela-Fernández; Isabel Puigdomènech; Laura de Armas-Rillo; José-David Machado
Journal:  Commun Integr Biol       Date:  2011-07-01

Review 3.  The ESCRT complexes.

Authors:  James H Hurley
Journal:  Crit Rev Biochem Mol Biol       Date:  2010-07-23       Impact factor: 8.250

4.  ESCRT-0 assembles as a heterotetrameric complex on membranes and binds multiple ubiquitinylated cargoes simultaneously.

Authors:  Jonathan R Mayers; Ian Fyfe; Amber L Schuh; Edwin R Chapman; J Michael Edwardson; Anjon Audhya
Journal:  J Biol Chem       Date:  2010-12-30       Impact factor: 5.157

5.  High CHMP4B expression is associated with accelerated cell proliferation and resistance to doxorubicin in hepatocellular carcinoma.

Authors:  Baoying Hu; Dawei Jiang; Yuyan Chen; Lixian Wei; Shusen Zhang; Fengbo Zhao; Runzhou Ni; Cuihua Lu; Chunhua Wan
Journal:  Tumour Biol       Date:  2015-02-11

Review 6.  The ESCRT machinery at a glance.

Authors:  Thomas Wollert; Dong Yang; Xuefeng Ren; Hyung Ho Lee; Young Jun Im; James H Hurley
Journal:  J Cell Sci       Date:  2009-07-01       Impact factor: 5.285

Review 7.  Cell biology of the ESCRT machinery.

Authors:  Phyllis I Hanson; Soomin Shim; Samuel A Merrill
Journal:  Curr Opin Cell Biol       Date:  2009-06-26       Impact factor: 8.382

8.  ESCRT-II coordinates the assembly of ESCRT-III filaments for cargo sorting and multivesicular body vesicle formation.

Authors:  David Teis; Suraj Saksena; Bret L Judson; Scott D Emr
Journal:  EMBO J       Date:  2010-02-04       Impact factor: 11.598

9.  Genetic modifiers of abnormal organelle biogenesis in a Drosophila model of BLOC-1 deficiency.

Authors:  Verónica T Cheli; Richard W Daniels; Ruth Godoy; Diego J Hoyle; Vasundhara Kandachar; Marta Starcevic; Julian A Martinez-Agosto; Stephen Poole; Aaron DiAntonio; Vett K Lloyd; Henry C Chang; David E Krantz; Esteban C Dell'Angelica
Journal:  Hum Mol Genet       Date:  2009-12-16       Impact factor: 6.150

Review 10.  Membrane fission reactions of the mammalian ESCRT pathway.

Authors:  John McCullough; Leremy A Colf; Wesley I Sundquist
Journal:  Annu Rev Biochem       Date:  2013-03-18       Impact factor: 23.643
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