Literature DB >> 19141131

Breast cancer in the elderly: retrospective study on diagnosis and treatment according to national guidelines.

Marije E Hamaker1, W H Schreurs, Jeroen M Uppelschoten, Carolien H Smorenburg.   

Abstract

We set out to investigate the level of accordance of diagnosis and treatment of elderly breast cancer patients with national guidelines and to study predictors of deviation. Data on patient and tumor variables were collected from charts of 166 patients aged 70 years and older, diagnosed at our hospital in 2002-2004. Diagnostic work-up and treatment were compared with guidelines and reasons for deviation were recorded; 122 (74%) patients were diagnosed and treated in accordance with guidelines. Diagnosis was incomplete in 19 patients (11%). Surgery, radiotherapy, and hormonal therapy were withheld in 19 (11%), 11 (7%), and 9 (5%) patients, respectively. Guideline deviation was motivated in 18 patients (11%) (comorbidity n=11, patients' preferences n=5, age n=2), unmotivated in 18 (11%), and undeliberate in 8 (5%). Our study demonstrates that deviation from guidelines in elderly breast cancer patients mainly occurs due to a deliberate adjustment to patient's comorbidity and preference.

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Year:  2009        PMID: 19141131     DOI: 10.1111/j.1524-4741.2008.00667.x

Source DB:  PubMed          Journal:  Breast J        ISSN: 1075-122X            Impact factor:   2.431


  7 in total

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4.  The impact of adjuvant radiotherapy on the survival of primary breast cancer patients: a retrospective multicenter cohort study of 8935 subjects.

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Review 5.  The impact of comorbidity on cancer survival: a review.

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6.  Guideline concordant therapy prolongs survival in HER2-positive breast cancer patients: results from a large population-based cohort of a cancer registry.

Authors:  E C Inwald; O Ortmann; F Zeman; M Koller; F Hofstädter; M Gerstenhauer; M Klinkhammer-Schalke
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7.  Adherence to treatment guidelines and survival in triple-negative breast cancer: a retrospective multi-center cohort study with 9,156 patients.

Authors:  Lukas Schwentner; Achim Wöckel; Jochem König; Wolfgang Janni; Florian Ebner; Maria Blettner; Rolf Kreienberg; Reyn Van Ewijk
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  7 in total

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