PURPOSE: This study aimed to verify the low complication rates (0% to 11%) previously reported in cranial reconstruction using hard-tissue replacement patient-matched implant (HTR-PMI). PATIENTS AND METHODS: A 3-year multidisciplinary experience involving 21 patients undergoing HTR-PMI reconstruction of large cranial defects was reviewed. Complications were defined as implant exposure, implant infection, or soft-tissue infection. RESULTS: A statistically higher rate of complications was observed, compared with previous series (P= .043). We also determined whether previous bone infection, a history of diabetes, or smoking were risk factors for the development of complications. Diabetes, smoking, and pre-existing bone/implant infections were not significant risk factors for HTR-PMI failure. The higher rate of complications can be partially attributed to a diverse and complicated patient population, with multiple comorbid conditions and various indications for HTR-PMI reconstruction. In particular, decompressive craniectomies in trauma patients can be risky indications for the use of HTR-PMI. CONCLUSION: Larger studies are suggested to verify our findings.
PURPOSE: This study aimed to verify the low complication rates (0% to 11%) previously reported in cranial reconstruction using hard-tissue replacement patient-matched implant (HTR-PMI). PATIENTS AND METHODS: A 3-year multidisciplinary experience involving 21 patients undergoing HTR-PMI reconstruction of large cranial defects was reviewed. Complications were defined as implant exposure, implant infection, or soft-tissue infection. RESULTS: A statistically higher rate of complications was observed, compared with previous series (P= .043). We also determined whether previous bone infection, a history of diabetes, or smoking were risk factors for the development of complications. Diabetes, smoking, and pre-existing bone/implant infections were not significant risk factors for HTR-PMI failure. The higher rate of complications can be partially attributed to a diverse and complicated patient population, with multiple comorbid conditions and various indications for HTR-PMI reconstruction. In particular, decompressive craniectomies in traumapatients can be risky indications for the use of HTR-PMI. CONCLUSION: Larger studies are suggested to verify our findings.
Authors: G Saponaro; P Doneddu; G Gasparini; Edoardo Staderini; R Boniello; M Todaro; G D'Amato; S Pelo; A Moro Journal: Childs Nerv Syst Date: 2019-07-31 Impact factor: 1.475
Authors: David B Kurland; Ariana Khaladj-Ghom; Jesse A Stokum; Brianna Carusillo; Jason K Karimy; Volodymyr Gerzanich; Juan Sahuquillo; J Marc Simard Journal: Neurocrit Care Date: 2015-10 Impact factor: 3.210