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Literature DB >> 19133299

The influence of calcium signaling on the regulation of alternative splicing.

Abstract

In this review the influence of calcium signaling on the regulation of alternative splicing is discussed with respect to its influence on cell- and developmental-specific expression of different isoforms of the plasma membrane calcium pump (PMCA). In a second part the possibility is discussed that due to the interaction of the calcium-binding protein ALG-2 with a spliceosomal regulator of alternative splicing, RBM22, Ca2+-signaling may thus influence its regulatory property.

Entities: Chemical Gene

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Year: 2008 PMID： 19133299 DOI： 10.1016/j.bbamcr.2008.12.006

Source DB: PubMed Journal: Biochim Biophys Acta ISSN： 0006-3002

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Cited

8 in total

Review 1. Emerging mechanisms and consequences of calcium regulation of alternative splicing in neurons and endocrine cells.

Authors: Aleh Razanau; Jiuyong Xie
Journal: Cell Mol Life Sci Date: 2013-06-26 Impact factor: 9.261

2. Exon skipping as a therapeutic strategy applied to an RYR1 mutation with pseudo-exon inclusion causing a severe core myopathy.

Authors: John Rendu; Julie Brocard; Eric Denarier; Nicole Monnier; France Piétri-Rouxel; Cyriaque Beley; Nathalie Roux-Buisson; Brigitte Gilbert-Dussardier; Marie José Perez; Norma Romero; Luis Garcia; Joël Lunardi; Julien Fauré; Anne Fourest-Lieuvin; Isabelle Marty
Journal: Hum Gene Ther Date: 2013-07 Impact factor: 5.695

Review 3. Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses.

Authors: Joachim Krebs; Jody Groenendyk; Marek Michalak
Journal: Neurochem Res Date: 2011-03-02 Impact factor: 3.996

4. Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition.

Authors: Tatsutoshi Inuzuka; Hironori Suzuki; Masato Kawasaki; Hideki Shibata; Soichi Wakatsuki; Masatoshi Maki
Journal: BMC Struct Biol Date: 2010-08-06

5. Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.

Authors: Takeshi Takahashi; Kyosuke Kojima; Wei Zhang; Kanae Sasaki; Masaru Ito; Hironori Suzuki; Masato Kawasaki; Soichi Wakatsuki; Terunao Takahara; Hideki Shibata; Masatoshi Maki
Journal: Int J Mol Sci Date: 2015-02-06 Impact factor: 5.923

The influence of calcium signaling on the regulation of alternative splicing.

Review 1. Emerging mechanisms and consequences of calcium regulation of alternative splicing in neurons and endocrine cells.

2. Exon skipping as a therapeutic strategy applied to an RYR1 mutation with pseudo-exon inclusion causing a severe core myopathy.

Review 3. Ca2+-signaling, alternative splicing and endoplasmic reticulum stress responses.

4. Molecular basis for defect in Alix-binding by alternatively spliced isoform of ALG-2 (ALG-2DeltaGF122) and structural roles of F122 in target recognition.

5. Structural analysis of the complex between penta-EF-hand ALG-2 protein and Sec31A peptide reveals a novel target recognition mechanism of ALG-2.

6. Multiple Calcium Export Exchangers and Pumps Are a Prominent Feature of Enamel Organ Cells.

Review 7. Endoplasmic Reticulum-Mitochondria Crosstalk and Beta-Cell Destruction in Type 1 Diabetes.

Review 8. RBM22, a Key Player of Pre-mRNA Splicing and Gene Expression Regulation, Is Altered in Cancer.