Literature DB >> 19127305

Effects of in utero antiepileptic drug exposure.

Kimford J Meador1.   

Abstract

Recent studies demonstrate an increased teratogenic risk for valproate and a probable increased risk for phenobarbital. Carbamazepine and lamotrigine appear relatively safe; however, results are inconclusive concerning a specific risk for cleft lip/palate for both drugs as well as a dose-dependent effect for malformations associated with lamotrigine. Data regarding teratogenic risks for other antiepileptic drugs are inadequate. Additional studies are needed to delineate further the risks for all antiepileptic drugs and determine the underlying mechanisms.

Entities:  

Year:  2008        PMID： 19127305      PMCID： PMC2610228          DOI： 10.1111/j.1535-7511.2008.00273.x

Source DB:  PubMed          Journal:  Epilepsy Curr        ISSN： 1535-7511            Impact factor:   7.500


  32 in total

1.  Malformation risks of antiepileptic drugs in pregnancy: a prospective study from the UK Epilepsy and Pregnancy Register.

Authors:  J Morrow; A Russell; E Guthrie; L Parsons; I Robertson; R Waddell; B Irwin; R C McGivern; P J Morrison; J Craig
Journal:  J Neurol Neurosurg Psychiatry       Date:  2005-09-12       Impact factor: 10.154

2.  Foetal malformations and seizure control: 52 months data of the Australian Pregnancy Registry.

Authors:  F J E Vajda; A Hitchcock; J Graham; C Solinas; T J O'Brien; C M Lander; M J Eadie
Journal:  Eur J Neurol       Date:  2006-06       Impact factor: 6.089

3.  Sulthiame but not levetiracetam exerts neurotoxic effect in the developing rat brain.

Authors:  Daniela Manthey; Stella Asimiadou; Vanya Stefovska; Angela M Kaindl; Jessica Fassbender; Chrysanthy Ikonomidou; Petra Bittigau
Journal:  Exp Neurol       Date:  2005-06       Impact factor: 5.330

4.  Ethanol-induced apoptotic neurodegeneration and fetal alcohol syndrome.

Authors:  C Ikonomidou; P Bittigau; M J Ishimaru; D F Wozniak; C Koch; K Genz; M T Price; V Stefovska; F Hörster; T Tenkova; K Dikranian; J W Olney
Journal:  Science       Date:  2000-02-11       Impact factor: 47.728

5.  Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register.

Authors:  S Hunt; J Craig; A Russell; E Guthrie; L Parsons; I Robertson; R Waddell; B Irwin; P J Morrison; J Morrow
Journal:  Neurology       Date:  2006-11-28       Impact factor: 9.910

6.  In utero exposure to phenobarbital and intelligence deficits in adult men.

Authors:  J M Reinisch; S A Sanders; E L Mortensen; D B Rubin
Journal:  JAMA       Date:  1995-11-15       Impact factor: 56.272

Review 7.  Pregnancy outcomes in women with epilepsy: a systematic review and meta-analysis of published pregnancy registries and cohorts.

Authors:  Kimford Meador; Matthew W Reynolds; Sheila Crean; Kyle Fahrbach; Corey Probst
Journal:  Epilepsy Res       Date:  2008-06-18       Impact factor: 3.045

8.  The outcome of pregnancy following topiramate treatment: a study on 52 pregnancies.

Authors:  Asher Ornoy; Naama Zvi; Judy Arnon; Rebecka Wajnberg; Svetlana Shechtman; Orna Diav-Citrin
Journal:  Reprod Toxicol       Date:  2008-03-16       Impact factor: 3.143

9.  Increased frequency of isolated cleft palate in infants exposed to lamotrigine during pregnancy.

Authors:  L B Holmes; E J Baldwin; C R Smith; E Habecker; L Glassman; S L Wong; D F Wyszynski
Journal:  Neurology       Date:  2008-04-30       Impact factor: 9.910

10.  Antiepileptic drug-induced neuronal cell death in the immature brain: effects of carbamazepine, topiramate, and levetiracetam as monotherapy versus polytherapy.

Authors:  Jinsook Kim; Alexei Kondratyev; Karen Gale
Journal:  J Pharmacol Exp Ther       Date:  2007-07-16       Impact factor: 4.030
View more
  9 in total

1.  Treatment options in juvenile myoclonic epilepsy.

Authors:  Laura Mantoan; Matthew Walker
Journal:  Curr Treat Options Neurol       Date:  2011-08       Impact factor: 3.598

Review 2.  Neonatal Adaptation Issues After Maternal Exposure to Prescription Drugs: Withdrawal Syndromes and Residual Pharmacological Effects.

Authors:  Irma Convertino; Alice Capogrosso Sansone; Alessandra Marino; Maria T Galiulo; Stefania Mantarro; Luca Antonioli; Matteo Fornai; Corrado Blandizzi; Marco Tuccori
Journal:  Drug Saf       Date:  2016-10       Impact factor: 5.606

3.  A description of sodium valproate, lamotrigine and levetiracetam consumption in the Western Cape public sector.

Authors:  Nicole Keuler; Yasmina Johnson; Renier Coetzee
Journal:  S Afr Fam Pract (2004)       Date:  2022-06-02

4.  Sodium valproate exposure during the brain growth spurt transiently impairs spatial learning in prepubertal rats.

Authors:  Cláudio C Filgueiras; Fernanda Pohl-Guimarães; Thomas E Krahe; Alexandre E Medina
Journal:  Pharmacol Biochem Behav       Date:  2012-11-21       Impact factor: 3.533

5.  Epilepsy drugs and effects on fetal development: Potential mechanisms.

Authors:  Leila Etemad; Mohammad Moshiri; Seyed Adel Moallem
Journal:  J Res Med Sci       Date:  2012-09       Impact factor: 1.852

6.  Teratogenicity of Antiepileptic Drugs.

Authors:  Betül Tekin Güveli; Rasim Özgür Rosti; Alper Güzeltaş; Elif Bahar Tuna; Dilek Ataklı; Serra Sencer; Ensar Yekeler; Hülya Kayserili; Ahmet Dirican; Nerses Bebek; Betül Baykan; Ayşen Gökyiğit; Candan Gürses
Journal:  Clin Psychopharmacol Neurosci       Date:  2017-02-28       Impact factor: 2.582

Review 7.  An Overview of the Main Genetic, Epigenetic and Environmental Factors Involved in Autism Spectrum Disorder Focusing on Synaptic Activity.

Authors:  Elena Masini; Eleonora Loi; Ana Florencia Vega-Benedetti; Marinella Carta; Giuseppe Doneddu; Roberta Fadda; Patrizia Zavattari
Journal:  Int J Mol Sci       Date:  2020-11-05       Impact factor: 5.923

8.  Teratogenic effects of pregabalin in mice.

Authors:  Leila Etemad; Afshar Mohammad; Amir Hooshang Mohammadpour; Nasser Vahdati Mashhadi; Seyed Adel Moallem
Journal:  Iran J Basic Med Sci       Date:  2013-10       Impact factor: 2.699

9.  Understanding and Responding to Prescribing Patterns of Sodium Valproate-Containing Medicines in Pregnant Women and Women of Childbearing Age in Western Cape, South Africa.

Authors:  Ushma Mehta; Mariette Smith; Emma Kalk; Helen Hayes; Annoesjka Swart; Lawrence Tucker; Renier Coetzee; Andrew Boulle; Marc Blockman
Journal:  Drug Saf       Date:  2021-01       Impact factor: 5.606
  9 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.