Literature DB >> 17130430

Levetiracetam in pregnancy: preliminary experience from the UK Epilepsy and Pregnancy Register.

S Hunt1, J Craig, A Russell, E Guthrie, L Parsons, I Robertson, R Waddell, B Irwin, P J Morrison, J Morrow.   

Abstract

It is not known whether the antiepileptic drug (AED) levetiracetam can be used safely in human pregnancy. As part of a study to determine the risks of major congenital malformations (MCMs) for infants exposed to AEDs in utero, we identified all cases exposed to levetiracetam. Three of 117 exposed pregnancies had an MCM (2.7%; 95% CI 0.9% to 7.7%); all 3 were exposed to other AEDs.

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Year:  2006        PMID: 17130430     DOI: 10.1212/01.wnl.0000244491.48937.55

Source DB:  PubMed          Journal:  Neurology        ISSN: 0028-3878            Impact factor:   9.910


  25 in total

1.  Treatment options in juvenile myoclonic epilepsy.

Authors:  Laura Mantoan; Matthew Walker
Journal:  Curr Treat Options Neurol       Date:  2011-08       Impact factor: 3.598

2.  Effects of in utero antiepileptic drug exposure.

Authors:  Kimford J Meador
Journal:  Epilepsy Curr       Date:  2008 Nov-Dec       Impact factor: 7.500

3.  Levetiracetam: more evidence of safety in pregnancy.

Authors:  Mohamad Koubeissi
Journal:  Epilepsy Curr       Date:  2013-11       Impact factor: 7.500

Review 4.  Pregnancy registries: what do they mean to clinical practice?

Authors:  Elizabeth Gerard; Alison M Pack
Journal:  Curr Neurol Neurosci Rep       Date:  2008-07       Impact factor: 5.081

5.  Does increased levetiracetam clearance during pregnancy require planned intervention?

Authors:  Bassel W Abou-Khalil
Journal:  Epilepsy Curr       Date:  2008 May-Jun       Impact factor: 7.500

Review 6.  Do lamotrigine and levetiracetam solve the problem of using sodium valproate in women with epilepsy?

Authors:  John J Craig
Journal:  Obstet Med       Date:  2012-02-20

Review 7.  Pregnancy outcomes in women with epilepsy: a systematic review and meta-analysis of published pregnancy registries and cohorts.

Authors:  Kimford Meador; Matthew W Reynolds; Sheila Crean; Kyle Fahrbach; Corey Probst
Journal:  Epilepsy Res       Date:  2008-06-18       Impact factor: 3.045

Review 8.  Managing epilepsy in women of childbearing age.

Authors:  Pamela M Crawford
Journal:  Drug Saf       Date:  2009       Impact factor: 5.606

Review 9.  Antiepileptic drugs during pregnancy: what is known and which AEDs seem to be safest?

Authors:  Page B Pennell
Journal:  Epilepsia       Date:  2008-12       Impact factor: 5.864

10.  Review of levetiracetam, with a focus on the extended release formulation, as adjuvant therapy in controlling partial-onset seizures.

Authors:  Carol M Ulloa; Allen Towfigh; Joseph Safdieh
Journal:  Neuropsychiatr Dis Treat       Date:  2009-09-15       Impact factor: 2.570

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