Literature DB >> 19118870

HLA class II and autoimmunity: epitope selection vs differential expression.

Brigitte Müller-Hilke1.   

Abstract

Autoimmune diseases like rheumatoid arthritis (RA), multiple sclerosis, psoriasis and insulin-dependent diabetes mellitus are subject to a complex pathogenesis controlled by multiple genes and numerous environmental factors. The strongest genetic association is with certain HLA class II haplotypes and we here summarize the evidence supporting differential expression as a mechanism supporting the autoimmune process.

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Year:  2008        PMID: 19118870     DOI: 10.1016/j.acthis.2008.11.011

Source DB:  PubMed          Journal:  Acta Histochem        ISSN: 0065-1281            Impact factor:   2.479


  5 in total

Review 1.  Unraveling the genetic component of systemic sclerosis.

Authors:  José Ezequiel Martín; Lara Bossini-Castillo; Javier Martín
Journal:  Hum Genet       Date:  2012-01-05       Impact factor: 4.132

2.  Anti-NMDA-receptor encephalitis in a 3 year old patient with chromosome 6p21.32 microdeletion including the HLA cluster.

Authors:  Helene Verhelst; Patrick Verloo; Karlien Dhondt; Boel De Paepe; Björn Menten; Josep Dalmau; Rudy Van Coster
Journal:  Eur J Paediatr Neurol       Date:  2010-08-06       Impact factor: 3.140

3.  Membranal and Blood-Soluble HLA Class II Peptidome Analyses Using Data-Dependent and Independent Acquisition.

Authors:  Danilo Ritz; Emiliano Sani; Hanna Debiec; Pierre Ronco; Dario Neri; Tim Fugmann
Journal:  Proteomics       Date:  2018-03-14       Impact factor: 3.984

4.  Comparison of hematopoietic stem cells derived from fresh and cryopreserved whole cord blood in the generation of humanized mice.

Authors:  Johanna Scholbach; Anett Schulz; Florian Westphal; Dietmar Egger; Anja Kathrin Wege; Ina Patties; Margarethe Köberle; Ulrich Sack; Franziska Lange
Journal:  PLoS One       Date:  2012-10-11       Impact factor: 3.240

5.  Inhibition of acid ceramidase regulates MHC class II antigen presentation and suppression of autoimmune arthritis.

Authors:  Dan Zhao; Laela M Hajiaghamohseni; Xiang Liu; Zdzislaw M Szulc; Aiping Bai; Alicja Bielawska; James S Norris; Sakamuri V Reddy; Yusuf A Hannun; Azizul Haque
Journal:  Cytokine       Date:  2020-07-29       Impact factor: 3.861

  5 in total

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