Literature DB >> 19117558

30 years of polytrauma care: An analysis of the change in strategies and results of 4849 cases treated at a single institution.

Christian Probst1, Hans-Christoph Pape, Frank Hildebrand, Gerd Regel, Lutz Mahlke, Peter Giannoudis, Christian Krettek, Martin Rolf Wolfgang Grotz.   

Abstract

The quality and progress of treatment of 4849 multiple trauma patients treated at one institution was reviewed retrospectively. Three periods, 1975-1984 (decade I; n=1469) and 1985-1994 (decade II; n=1937) and 1995-2004 (decade III; n=1443) were compared. 65% of multiple trauma patients had cerebral injuries, 58% thoracic trauma and 81% extremity fractures (37% open injuries). Injury combinations decreased during all decades with head/extremity injuries being the most common combination. Throughout the three decades pre-hospital care became more aggressive with an increase of intravenous fluid resuscitation (I: 80%, II: 97%, III: 98%). Chest tube insertion decreased after an initial increase (I: 41%, II: 83%, III: 27%) as well as intubation (I: 82%, II: 94%, III: 59%). Rescue times were progressively shortened. For initial clinical diagnosis of massive abdominal haemorrhage ultrasound (I: 17%, II: 92%, III: 97%) replaced peritoneal lavage (I: 44%, II: 28%, III: 0%). CT-scans were used more frequently for the initial diagnosis of head injuries and other injuries to the trunk throughout the observation time. With regard to complications, acute renal failure decreased by half (I: 8.4%; II: 3.7%; III: 3.9%), ARDS initially decreased but increased again in the last decade (I: 18.1%, II: 13.4%, III: 15.3%), whereas the rate of multiple organ dysfunction syndrome (MODS) increased continuously (I: 14.2%, II: 18.9%, III: 19.8%) probably due to a decline of the mortality rate from 37% in the first to 22% in the second and 18% in the third decade and parallel increase of the time of death. These treatment results summarise the enormous clinical effort as well as medical progress in polytrauma management over the past 30 years. Further reduction of mortality is desirable, but probably only possible when immediate causal therapy of later posttraumatic organ failure can be established.

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Year:  2008        PMID: 19117558     DOI: 10.1016/j.injury.2008.10.004

Source DB:  PubMed          Journal:  Injury        ISSN: 0020-1383            Impact factor:   2.586


  61 in total

1.  The influence of coagulation and inflammation research on the improvement of polytrauma care.

Authors:  M Perl; M Huber-Lang; F Gebhard
Journal:  Eur J Trauma Emerg Surg       Date:  2011-11-09       Impact factor: 3.693

Review 2.  Protocols for massive blood transfusion: when and why, and potential complications.

Authors:  E Guerado; A Medina; M I Mata; J M Galvan; M L Bertrand
Journal:  Eur J Trauma Emerg Surg       Date:  2015-12-09       Impact factor: 3.693

3.  [Importance of air ambulances for the care of the severely injured].

Authors:  U Schweigkofler; C Reimertz; R Lefering; R Hoffmann
Journal:  Unfallchirurg       Date:  2015-03       Impact factor: 1.000

Review 4.  [Polytrauma and concomitant traumatic brain injury : The role of the trauma surgeon].

Authors:  A Antoni; T Heinz; J Leitgeb
Journal:  Unfallchirurg       Date:  2017-09       Impact factor: 1.000

Review 5.  [The "time" factor. Its impact in pathophysiology and therapy of multiple trauma].

Authors:  V Bogner; W Mutschler; P Biberthaler
Journal:  Unfallchirurg       Date:  2009-10       Impact factor: 1.000

6.  Human Myeloid-derived Suppressor Cells are Associated With Chronic Immune Suppression After Severe Sepsis/Septic Shock.

Authors:  Brittany Mathias; Amber L Delmas; Tezcan Ozrazgat-Baslanti; Erin L Vanzant; Benjamin E Szpila; Alicia M Mohr; Frederick A Moore; Scott C Brakenridge; Babette A Brumback; Lyle L Moldawer; Philip A Efron
Journal:  Ann Surg       Date:  2017-04       Impact factor: 12.969

7.  Trauma-related preventable deaths in Berlin 2010: need to change prehospital management strategies and trauma management education.

Authors:  C Kleber; M T Giesecke; M Tsokos; N P Haas; C T Buschmann
Journal:  World J Surg       Date:  2013-05       Impact factor: 3.352

Review 8.  The future of murine sepsis and trauma research models.

Authors:  Philip A Efron; Alicia M Mohr; Frederick A Moore; Lyle L Moldawer
Journal:  J Leukoc Biol       Date:  2015-06-01       Impact factor: 4.962

9.  Development of a genomic metric that can be rapidly used to predict clinical outcome in severely injured trauma patients.

Authors:  Alex G Cuenca; Lori F Gentile; M Cecilia Lopez; Ricardo Ungaro; Huazhi Liu; Wenzhong Xiao; Junhee Seok; Michael N Mindrinos; Darwin Ang; Tezcan Ozrazgat Baslanti; Azra Bihorac; Philip A Efron; Joseph Cuschieri; H Shaw Warren; Ronald G Tompkins; Ronald V Maier; Henry V Baker; Lyle L Moldawer
Journal:  Crit Care Med       Date:  2013-05       Impact factor: 7.598

10.  Time-based trauma-related mortality patterns in a newly created trauma system.

Authors:  Husham Abdelrahman; Ayman El-Menyar; Hassan Al-Thani; Rafael Consunji; Ahmad Zarour; Ruben Peralta; Ashok Parchani; Rifat Latifi
Journal:  World J Surg       Date:  2014-11       Impact factor: 3.352

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