Azadeh Rakhshan1, Hanieh Zham, Mehdi Kazempour. 1. Department of Pathology, Shohada Hospital, Shaheed Beheshti University of Medical Sciences, Tehran, Iran. azadehrakhshan@yahoo.com
Abstract
PURPOSE: Accurate frozen section diagnosis is necessary for appropriate surgical management. In this study, we planned to determine the accuracy of frozen section diagnosis in our center and to study the factors which may influence the accuracy of frozen section diagnosis of ovarian tumors. METHODS: In the present study, frozen section diagnosis of adnexal masses in 282 patients was compared with permanent section diagnosis as the gold standard. RESULTS: The overall accuracy of frozen section diagnosis was 95.7%. The sensitivity of frozen section diagnosis for benign, borderline and malignant lesions was 99, 60, and 92%, respectively. The tumor size in discrepant cases was larger than the concordant cases, however no association between mucinous histology and inaccurate diagnosis was found. The sensitivities of gross examination and clinical data in distinguishing benign from non-benign lesions were 93 and 70%, respectively. CONCLUSION: Frozen section is a reliable method for surgical management of patients with adnexal masses. Gross examination and clinical data are two valuable parts of intraoperative consultation.
PURPOSE: Accurate frozen section diagnosis is necessary for appropriate surgical management. In this study, we planned to determine the accuracy of frozen section diagnosis in our center and to study the factors which may influence the accuracy of frozen section diagnosis of ovarian tumors. METHODS: In the present study, frozen section diagnosis of adnexal masses in 282 patients was compared with permanent section diagnosis as the gold standard. RESULTS: The overall accuracy of frozen section diagnosis was 95.7%. The sensitivity of frozen section diagnosis for benign, borderline and malignant lesions was 99, 60, and 92%, respectively. The tumor size in discrepant cases was larger than the concordant cases, however no association between mucinous histology and inaccurate diagnosis was found. The sensitivities of gross examination and clinical data in distinguishing benign from non-benign lesions were 93 and 70%, respectively. CONCLUSION: Frozen section is a reliable method for surgical management of patients with adnexal masses. Gross examination and clinical data are two valuable parts of intraoperative consultation.
Authors: Salvatore Gizzo; Roberto Berretta; Stefania Di Gangi; Maria Guido; Giuliano Carlo Zanni; Ilaria Franceschetti; Michela Quaranta; Mario Plebani; Giovanni Battista Nardelli; Tito Silvio Patrelli Journal: Biomed Res Int Date: 2014-11-05 Impact factor: 3.411
Authors: Nithya D G Ratnavelu; Andrew P Brown; Susan Mallett; Rob J P M Scholten; Amit Patel; Christina Founta; Khadra Galaal; Paul Cross; Raj Naik Journal: Cochrane Database Syst Rev Date: 2016-03-01