PURPOSE: The purpose of this study was to compare the depiction of intracranial aneurysms by 3D time-of-flight (TOF) magnetic resonance angiography (MRA) at 7 Tesla (T) with the clinical standard TOF MRA at 1.5 T and with digital subtraction angiography (DSA). MATERIALS AND METHODS: 7 T and 1.5 T TOF MRA images optimized for both field strengths were compared in ten patients with an unruptured intracranial aneurysm. Two blinded neuroradiologists independently rated the image quality of the dome, the neck, and the vessel of origin of all aneurysms in MRA source and maximum intensity projection (MIP) images. DSA was obtained in all subjects and served as reference standard. The mean values of image quality were compared by Wilcoxon signed rank test. In all patients the number and location of the aneurysms was confirmed by DSA. RESULTS: Both readers identified twelve aneurysms in ten patients in 7 T, 1.5 T TOF MRA and DSA. The image quality of the aneurysm dome was rated higher in 8 of 12 aneurysms and the image quality of the aneurysm neck was superior in 9 of 12 aneurysms at 7 T TOF MRA compared to 1.5 T TOF MRA. The depiction of the parent vessel was graded almost equally by both readers. CONCLUSION: Our initial results indicate that image quality of intracranial aneurysms may benefit from the increased spatial resolution of 7 T TOF MRA compared with 1.5 T TOF MRA. Tailored scan protocols and optimized radiofrequency head coils are needed to further improve the image quality of 7 T TOF MRA.
PURPOSE: The purpose of this study was to compare the depiction of intracranial aneurysms by 3D time-of-flight (TOF) magnetic resonance angiography (MRA) at 7 Tesla (T) with the clinical standard TOF MRA at 1.5 T and with digital subtraction angiography (DSA). MATERIALS AND METHODS: 7 T and 1.5 T TOF MRA images optimized for both field strengths were compared in ten patients with an unruptured intracranial aneurysm. Two blinded neuroradiologists independently rated the image quality of the dome, the neck, and the vessel of origin of all aneurysms in MRA source and maximum intensity projection (MIP) images. DSA was obtained in all subjects and served as reference standard. The mean values of image quality were compared by Wilcoxon signed rank test. In all patients the number and location of the aneurysms was confirmed by DSA. RESULTS: Both readers identified twelve aneurysms in ten patients in 7 T, 1.5 T TOF MRA and DSA. The image quality of the aneurysm dome was rated higher in 8 of 12 aneurysms and the image quality of the aneurysm neck was superior in 9 of 12 aneurysms at 7 T TOF MRA compared to 1.5 T TOF MRA. The depiction of the parent vessel was graded almost equally by both readers. CONCLUSION: Our initial results indicate that image quality of intracranial aneurysms may benefit from the increased spatial resolution of 7 T TOF MRA compared with 1.5 T TOF MRA. Tailored scan protocols and optimized radiofrequency head coils are needed to further improve the image quality of 7 T TOF MRA.
Authors: Lale Umutlu; Stephan Orzada; Sonja Kinner; Stefan Maderwald; Irina Brote; Andreas K Bitz; Oliver Kraff; Susanne C Ladd; Gerald Antoch; Mark E Ladd; Harald H Quick; Thomas C Lauenstein Journal: Eur Radiol Date: 2010-09-25 Impact factor: 5.315
Authors: M J van Amerongen; H D Boogaarts; J de Vries; A L M Verbeek; F J A Meijer; M Prokop; R H M A Bartels Journal: AJNR Am J Neuroradiol Date: 2013-09-05 Impact factor: 3.825
Authors: Karsten H Wrede; Philipp Dammann; Sören Johst; Christoph Mönninghoff; Marc Schlamann; Stefan Maderwald; I Erol Sandalcioglu; Mark E Ladd; Michael Forsting; Ulrich Sure; Lale Umutlu Journal: Eur Radiol Date: 2015-06-17 Impact factor: 5.315
Authors: Lale Umutlu; Oliver Kraff; Anja Fischer; Sonja Kinner; Stefan Maderwald; Kai Nassenstein; Felix Nensa; Johannes Grüneisen; Stephan Orzada; Andreas K Bitz; Michael Forsting; Mark E Ladd; Thomas C Lauenstein Journal: Eur Radiol Date: 2013-05-04 Impact factor: 5.315
Authors: Karsten H Wrede; Toshinori Matsushige; Sophia L Goericke; Bixia Chen; Lale Umutlu; Harald H Quick; Mark E Ladd; Sören Johst; Michael Forsting; Ulrich Sure; Marc Schlamann Journal: Eur Radiol Date: 2016-03-18 Impact factor: 5.315
Authors: Sebastian Schmitter; Xiaoping Wu; Edward J Auerbach; Gregor Adriany; Josef Pfeuffer; Michael Hamm; Kâmil Uğurbil; Pierre-François van de Moortele Journal: Invest Radiol Date: 2014-05 Impact factor: 6.016
Authors: Giuseppe Barisano; Farshid Sepehrband; Samantha Ma; Kay Jann; Ryan Cabeen; Danny J Wang; Arthur W Toga; Meng Law Journal: Br J Radiol Date: 2018-11-01 Impact factor: 3.629