Literature DB >> 19111762

New concepts in atrial fibrillation: neural mechanisms and calcium dynamics.

Chung-Chuan Chou1, Peng-Sheng Chen.   

Abstract

Atrial fibrillation (AF) is a complex arrhythmia with multiple possible mechanisms. It requires a trigger for initiation and a favorable substrate for maintenance. Pulmonary vein myocardial sleeves have the potential to generate spontaneous activity, and this arrhythmogenic activity is surfaced by modulation of intracellular calcium dynamics. Direct autonomic nerve recordings in canine models show that simultaneous sympathovagal discharges are the most common triggers of paroxysmal atrial tachycardia and paroxysmal AF. Autonomic modulation as a potential therapeutic strategy has been targeted clinically and experimentally, but its effectiveness as an adjunctive therapeutic modality to catheter ablation of AF has been inconsistent. Further studies are warranted before application can be widely implied for therapies of clinical AF.

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Year:  2009        PMID： 19111762      PMCID： PMC2653219          DOI： 10.1016/j.ccl.2008.09.003

Source DB:  PubMed          Journal:  Cardiol Clin        ISSN： 0733-8651            Impact factor:   2.213


  74 in total

1.  PKA phosphorylation dissociates FKBP12.6 from the calcium release channel (ryanodine receptor): defective regulation in failing hearts.

Authors:  S O Marx; S Reiken; Y Hisamatsu; T Jayaraman; D Burkhoff; N Rosemblit; A R Marks
Journal:  Cell       Date:  2000-05-12       Impact factor: 41.582

2.  Neural mechanisms of paroxysmal atrial fibrillation and paroxysmal atrial tachycardia in ambulatory canines.

Authors:  Alex Y Tan; Shengmei Zhou; Masahiro Ogawa; Juan Song; Matthew Chu; Hongmei Li; Michael C Fishbein; Shien-Fong Lin; Lan S Chen; Peng-Sheng Chen
Journal:  Circulation       Date:  2008-08-12       Impact factor: 29.690

3.  Atrial fibrillation produced by prolonged rapid atrial pacing is associated with heterogeneous changes in atrial sympathetic innervation.

Authors:  J V Jayachandran; H J Sih; W Winkle; D P Zipes; G D Hutchins; J E Olgin
Journal:  Circulation       Date:  2000-03-14       Impact factor: 29.690

4.  Activation of inward rectifier potassium channels accelerates atrial fibrillation in humans: evidence for a reentrant mechanism.

Authors:  Felipe Atienza; Jesús Almendral; Javier Moreno; Ravi Vaidyanathan; Arkazdi Talkachou; Jérôme Kalifa; Angel Arenal; Julian P Villacastín; Esteban G Torrecilla; Ana Sánchez; Robert Ploutz-Snyder; José Jalife; Omer Berenfeld
Journal:  Circulation       Date:  2006-11-13       Impact factor: 29.690

5.  Neurocardiogenic mechanisms of unexplained syncope in idiopathic dilated cardiomyopathy.

Authors:  Efthimios G Livanis; Anna Kostopoulou; George N Theodorakis; Nikolitsa Aggelopoulou; Stamatis Adamopoulos; Dimitrios Degiannis; Dimitrios Th Kremastinos
Journal:  Am J Cardiol       Date:  2007-01-02       Impact factor: 2.778

6.  Ectopic atrial arrhythmias arising from canine thoracic veins during in vivo stellate ganglia stimulation.

Authors:  Alex Y Tan; Shengmei Zhou; Byung Chun Jung; Masahiro Ogawa; Lan S Chen; Michael C Fishbein; Peng-Sheng Chen
Journal:  Am J Physiol Heart Circ Physiol       Date:  2008-06-06       Impact factor: 4.733

7.  Left stellate ganglion and vagal nerve activity and cardiac arrhythmias in ambulatory dogs with pacing-induced congestive heart failure.

Authors:  Masahiro Ogawa; Shengmei Zhou; Alex Y Tan; Juan Song; Ghassan Gholmieh; Michael C Fishbein; Huai Luo; Robert J Siegel; Hrayr S Karagueuzian; Lan S Chen; Shien-Fong Lin; Peng-Sheng Chen
Journal:  J Am Coll Cardiol       Date:  2007-07-10       Impact factor: 24.094

8.  Pulmonary vein region ablation in experimental vagal atrial fibrillation: role of pulmonary veins versus autonomic ganglia.

Authors:  Kristina Lemola; Denis Chartier; Yung-Hsin Yeh; Marc Dubuc; Raymond Cartier; Andrew Armour; Michael Ting; Masao Sakabe; Akiko Shiroshita-Takeshita; Philippe Comtois; Stanley Nattel
Journal:  Circulation       Date:  2008-01-14       Impact factor: 29.690

9.  Mechanism underlying initiation of paroxysmal atrial flutter/atrial fibrillation by ectopic foci: a simulation study.

Authors:  Yunfan Gong; Fagen Xie; Kenneth M Stein; Alan Garfinkel; Calin A Culianu; Bruce B Lerman; David J Christini
Journal:  Circulation       Date:  2007-04-09       Impact factor: 29.690

10.  Intracellular calcium dynamics and acetylcholine-induced triggered activity in the pulmonary veins of dogs with pacing-induced heart failure.

Authors:  Chung-Chuan Chou; Bich Lien Nguyen; Alex Y Tan; Po-Cheng Chang; Hui-Ling Lee; Fun-Chung Lin; San-Jou Yeh; Michael C Fishbein; Shien-Fong Lin; Delon Wu; Ming-Shien Wen; Peng-Sheng Chen
Journal:  Heart Rhythm       Date:  2008-04-12       Impact factor: 6.343
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  11 in total

Review 1.  Atrial Fibrillation and Metabolic Syndrome: Understanding the Connection.

Authors:  Prabhat Kumar; Anil K Gehi
Journal:  J Atr Fibrillation       Date:  2012-10-06

Review 2.  Recent advances in the molecular pathophysiology of atrial fibrillation.

Authors:  Reza Wakili; Niels Voigt; Stefan Kääb; Dobromir Dobrev; Stanley Nattel
Journal:  J Clin Invest       Date:  2011-08-01       Impact factor: 14.808

Review 3.  Recent insights into the role of the autonomic nervous system in the creation of substrate for atrial fibrillation: implications for therapies targeting the atrial autonomic nervous system.

Authors:  Rishi Arora
Journal:  Circ Arrhythm Electrophysiol       Date:  2012-08-01

4.  Pulmonary vein isolation combined with spironolactone or renal sympathetic denervation in patients with chronic kidney disease, uncontrolled hypertension, paroxysmal atrial fibrillation, and a pacemaker.

Authors:  Márcio Galindo Kiuchi; Shaojie Chen; Neil Alexander Hoye; Helmut Pürerfellner
Journal:  J Interv Card Electrophysiol       Date:  2017-12-20       Impact factor: 1.900

Review 5.  Mechanisms of termination and prevention of atrial fibrillation by drug therapy.

Authors:  A J Workman; G L Smith; A C Rankin
Journal:  Pharmacol Ther       Date:  2011-02-18       Impact factor: 12.310

6.  Atrial Fibrillation (Part 1): Pathophysiology, Risk Factors, and Therapeutic Basis.

Authors:  Fatima Dumas Cintra; Marcio Jansen de Oliveira Figueiredo
Journal:  Arq Bras Cardiol       Date:  2021-01       Impact factor: 2.000

7.  NOX4-Dependent Hydrogen Peroxide Overproduction in Human Atrial Fibrillation and HL-1 Atrial Cells: Relationship to Hypertension.

Authors:  Jun Zhang; Ji Youn Youn; Antony Y Kim; Rafael J Ramirez; Ling Gao; Doan Ngo; Peng Chen; Jennifer Scovotti; Aman Mahajan; Hua Cai
Journal:  Front Physiol       Date:  2012-06-05       Impact factor: 4.566

8.  Generalized Poincaré Plots-A New Method for Evaluation of Regimes in Cardiac Neural Control in Atrial Fibrillation and Healthy Subjects.

Authors:  Mirjana M Platiša; Tijana Bojić; Siniša U Pavlović; Nikola N Radovanović; Aleksandar Kalauzi
Journal:  Front Neurosci       Date:  2016-02-16       Impact factor: 4.677

Review 9.  Atrial Fibrillation: The Science behind Its Defiance.

Authors:  Maureen E Czick; Christine L Shapter; David I Silverman
Journal:  Aging Dis       Date:  2016-10-01       Impact factor: 6.745

Review 10.  Synaptic Plasticity in Cardiac Innervation and Its Potential Role in Atrial Fibrillation.

Authors:  Jesse L Ashton; Rebecca A B Burton; Gil Bub; Bruce H Smaill; Johanna M Montgomery
Journal:  Front Physiol       Date:  2018-03-20       Impact factor: 4.566
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