Literature DB >> 19100807

Comparison of efficacy of commercial one dose and two dose PCV2 vaccines using a mixed PRRSV-PCV2-SIV clinical infection model 2-3-months post vaccination.

T Opriessnig1, A R Patterson, D M Madson, N Pal, P G Halbur.   

Abstract

The study objectives were to compare the duration of immunity of commercially available, one and two dose, killed porcine circovirus type 2 (PCV2) vaccines. Sixty, 3.5-week-old pigs were randomly divided into six treatment groups: one dose vaccines (FDAH-1, BIVI-1), two dose vaccines (Intervet-2, FDAH-2), and non-vaccinated negative and positive controls. Tissue homogenate challenge was conducted 63 (two doses) or 84 (one dose) days post vaccination. Viremia was reduced by 78.5% in pigs vaccinated with one dose and by 97.1% in pigs vaccinated with two dose products and overall microscopic lymphoid lesions were reduced by 78.7% and 81.8%, respectively.

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Year:  2008        PMID: 19100807     DOI: 10.1016/j.vaccine.2008.11.105

Source DB:  PubMed          Journal:  Vaccine        ISSN: 0264-410X            Impact factor:   3.641


  24 in total

1.  Porcine reproductive and respiratory syndrome virus infection at the time of porcine circovirus type 2 vaccination has no impact on vaccine efficacy.

Authors:  A Sinha; H G Shen; S Schalk; N M Beach; Y W Huang; P G Halbur; X J Meng; T Opriessnig
Journal:  Clin Vaccine Immunol       Date:  2010-10-06

2.  Comparison of four commercial one-dose porcine circovirus type 2 (PCV2) vaccines administered to pigs challenged with PCV2 and porcine reproductive and respiratory syndrome virus at 17 weeks postvaccination to control porcine respiratory disease complex under Korean field conditions.

Authors:  Changhoon Park; Hwi Won Seo; Kiwon Han; Chanhee Chae
Journal:  Clin Vaccine Immunol       Date:  2014-01-08

3.  Immune responses of piglets immunized by a recombinant plasmid containing porcine circovirus type 2 and porcine interleukin-18 genes.

Authors:  Guang-Lei Chen; Peng-Fei Fu; Lin-Qing Wang; Xin-Sheng Li; Hong-Ying Chen
Journal:  Viral Immunol       Date:  2014-12       Impact factor: 2.257

4.  Evaluation of commercial polyclonal- and monoclonal-antibody-based immunohistochemical tests for 2 genotypes of Porcine circovirus type 2 and comparison with in-situ hybridization assays.

Authors:  Hwi Won Seo; Kiwon Han; Yeonsu Oh; Ikjae Kang; Changhoon Park; Hye Eun Joo; Sung-Hoon Kim; Bog-Hieu Lee; Chanhee Chae
Journal:  Can J Vet Res       Date:  2014-07       Impact factor: 1.310

5.  Effects of an inactivated porcine circovirus type 2 (PCV2) vaccine on PCV2 virus shedding in semen from experimentally infected boars.

Authors:  Hwi Won Seo; Kiwon Han; Duyeol Kim; Yeonsu Oh; Ikjae Kang; Changhoon Park; Hyun Jang; Chanhee Chae
Journal:  Clin Vaccine Immunol       Date:  2011-05-25

6.  A Novel Porcine Circovirus Distantly Related to Known Circoviruses Is Associated with Porcine Dermatitis and Nephropathy Syndrome and Reproductive Failure.

Authors:  Rachel Palinski; Pablo Piñeyro; Pengcheng Shang; Fangfeng Yuan; Rui Guo; Ying Fang; Emily Byers; Ben M Hause
Journal:  J Virol       Date:  2016-12-16       Impact factor: 5.103

7.  A live-attenuated chimeric porcine circovirus type 2 (PCV2) vaccine is transmitted to contact pigs but is not upregulated by concurrent infection with porcine parvovirus (PPV) and porcine reproductive and respiratory syndrome virus (PRRSV) and is efficacious in a PCV2b-PRRSV-PPV challenge model.

Authors:  T Opriessnig; H G Shen; N Pal; S Ramamoorthy; Y W Huang; K M Lager; N M Beach; P G Halbur; X J Meng
Journal:  Clin Vaccine Immunol       Date:  2011-06-08

8.  Comparison of Porcine circovirus type 2 (PCV2) infection in light and heavy pigs of market age on farms with routine PCV2 vaccination.

Authors:  Kwang-Soo Lyoo; Han Soo Joo; Peter R Davies; Jeong Hee Han
Journal:  Can J Vet Res       Date:  2012-07       Impact factor: 1.310

9.  Short communication: a modified Vaccinia virus Ankara-based Porcine circovirus 2 vaccine elicits strong antibody response upon prime-boost homologous immunization in a preclinical model.

Authors:  Danielle Soares de Oliveira Daian E Silva; Edel Figueiredo Barbosa-Stancioli; Jordana Graziela Alves Coelho-Dos-Reis; Flávio Guimarães Da Fonseca
Journal:  Braz J Microbiol       Date:  2020-03-06       Impact factor: 2.476

10.  Porcine circovirus type 2 (PCV2)-infection and re-inoculation with homologous or heterologous strains: virological, serological, pathological and clinical effects in growing pigs.

Authors:  Tanja Opriessnig; John R Prickett; Darin M Madson; Hui-Gang Shen; Nicole M Juhan; Roman R Pogranichniy; Xiang-Jin Meng; Patrick G Halbur
Journal:  Vet Res       Date:  2010-01-18       Impact factor: 3.683

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