Literature DB >> 19096993

Antifungal triterpene glycosides from the sea cucumber Bohadschia marmorata.

Wei-Hua Yuan1, Yang-Hua Yi, Hai-Feng Tang, Bao-Shu Liu, Zeng-Lei Wang, Guo-Quan Sun, Wen Zhang, Ling Li, Peng Sun.   

Abstract

Four new holostan-type triterpene glycosides, marmoratoside A ( 1), 17 alpha-hydroxy impatienside A ( 2), marmoratoside B ( 3), 25-acetoxy bivittoside D ( 4), together with two known triterpene glycosides, impatienside A ( 5) and bivittoside D ( 6), were isolated from the sea cucumber Bohadschia Marmorata Jaeger. On the basis of spectroscopic analyses, including two-dimensional NMR techniques, and chemical reactions, the structures of the new triterpene glycosides were elucidated. Compounds 1, 2, 5, and 6 exhibited significant antifungal activity against six strains (0.70 < or = MIC (80) < or = 2.81 microM).

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Year:  2008        PMID： 19096993     DOI： 10.1055/s-0028-1088348

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  10 in total

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Journal:  Appl Microbiol Biotechnol       Date:  2014-02-23       Impact factor: 4.813

2.  Qualitative and quantitative saponin contents in five sea cucumbers from the Indian ocean.

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Journal:  Mar Drugs       Date:  2011-10-10       Impact factor: 6.085

Review 4.  The effects of marine carbohydrates and glycosylated compounds on human health.

Authors:  Hee-Kyoung Kang; Chang Ho Seo; Yoonkyung Park
Journal:  Int J Mol Sci       Date:  2015-03-16       Impact factor: 5.923

Review 5.  Marine pharmacology in 2009-2011: marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral activities; affecting the immune and nervous systems, and other miscellaneous mechanisms of action.

Authors:  Alejandro M S Mayer; Abimael D Rodríguez; Orazio Taglialatela-Scafati; Nobuhiro Fusetani
Journal:  Mar Drugs       Date:  2013-07-16       Impact factor: 5.118

Review 6.  Sea Cucumber Glycosides: Chemical Structures, Producing Species and Important Biological Properties.

Authors:  Muhammad Abdul Mojid Mondol; Hee Jae Shin; M Aminur Rahman; Mohamad Tofazzal Islam
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7.  Molecular Networking-Based Analysis of Cytotoxic Saponins from Sea Cucumber Holothuria atra.

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Journal:  Mar Drugs       Date:  2019-02-01       Impact factor: 5.118

Review 8.  Acetylated Triterpene Glycosides and Their Biological Activity from Holothuroidea Reported in the Past Six Decades.

Authors:  Yadollah Bahrami; Christopher M M Franco
Journal:  Mar Drugs       Date:  2016-08-04       Impact factor: 5.118

Review 9.  Pharmacological Potential of Sea Cucumbers.

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Journal:  Int J Mol Sci       Date:  2018-05-02       Impact factor: 5.923

10.  Distribution of Saponins in the Sea Cucumber Holothuria lessoni; the Body Wall Versus the Viscera, and Their Biological Activities.

Authors:  Yadollah Bahrami; Wei Zhang; Christopher M M Franco
Journal:  Mar Drugs       Date:  2018-11-01       Impact factor: 5.118
  10 in total

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