Literature DB >> 19096865

Pupil campimetry in patients with retinitis pigmentosa and functional visual field loss.

Karolína Skorkovská1, Holger Lüdtke, Helmut Wilhelm, Barbara Wilhelm.   

Abstract

BACKGROUND: The aim of our study was to test in a small series of cases if pupil perimetry can prove real concentric visual field loss in retinal degeneration and distinguish from feigned visual field loss.
METHODS: By means of infrared-video-pupillography, light responses to perimetric stimuli were recorded. The stimulus pattern consisted of 41 stimuli presented in the central 30 degrees visual field. Stimulus intensity was 140 cd/m(2). 5 healthy subjects, 6 patients with retinitis pigmentosa and 2 patients with suspected functional visual field loss were examined.
RESULTS: Pupil perimetry was able to reproduce the visual field in retinitis pigmentosa very well. Normal subjects and patients with suspected feigned visual field loss showed normal pupillomotor fields, different from the findings in retinitis pigmentosa.
CONCLUSIONS: This study provides sufficient evidence that pupil campimetry is applicable for differentiating between retinal dystrophy and functional concentric visual field loss. Possible residual light sensitivity of the blind retina due to melanopsin ganglion cells is obviously not sufficient to provide a pupillary light response to perimetric stimuli.

Entities:  

Mesh:

Year:  2008        PMID: 19096865     DOI: 10.1007/s00417-008-1015-0

Source DB:  PubMed          Journal:  Graefes Arch Clin Exp Ophthalmol        ISSN: 0721-832X            Impact factor:   3.117


  13 in total

1.  Comparison of pupil perimetry and visual perimetry in normal eyes: decibel sensitivity and variability.

Authors:  S Hong; J Narkiewicz; R H Kardon
Journal:  Invest Ophthalmol Vis Sci       Date:  2001-04       Impact factor: 4.799

2.  Diminished pupillary light reflex at high irradiances in melanopsin-knockout mice.

Authors:  R J Lucas; S Hattar; M Takao; D M Berson; R G Foster; K-W Yau
Journal:  Science       Date:  2003-01-10       Impact factor: 47.728

3.  Pupil campimetry in patients with visual field loss.

Authors:  R Schmid; H Luedtke; B J Wilhelm; H Wilhelm
Journal:  Eur J Neurol       Date:  2005-08       Impact factor: 6.089

4.  [Disturbances of the pupil reflex associated with lesions of the upper visual pathway (author's transl)].

Authors:  E Alexandridis; H Krastel; R Reuther
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1979-01-15

5.  [Pupillary light reflexes in Heredodegeneratio pigmentosa retinae].

Authors:  E Alexandridis; A Weddigen
Journal:  Albrecht Von Graefes Arch Klin Exp Ophthalmol       Date:  1971

6.  Pupil motor perimetry.

Authors:  R H Bresky; S Charles
Journal:  Am J Ophthalmol       Date:  1969-07       Impact factor: 5.258

7.  Cells in the pretectal olivary nucleus are in the pathway for the direct light reflex of the pupil in the rat.

Authors:  L J Trejo; C M Cicerone
Journal:  Brain Res       Date:  1984-05-21       Impact factor: 3.252

8.  Melanopsin-containing retinal ganglion cells: architecture, projections, and intrinsic photosensitivity.

Authors:  S Hattar; H W Liao; M Takao; D M Berson; K W Yau
Journal:  Science       Date:  2002-02-08       Impact factor: 47.728

9.  Luminance and darkness detectors in the olivary and posterior pretectal nuclei and their relationship to the pupillary light reflex in the rat. I. Studies with steady luminance levels.

Authors:  R J Clarke; H Ikeda
Journal:  Exp Brain Res       Date:  1985       Impact factor: 1.972

10.  Pupil perimetry in the diagnosis of functional visual field loss.

Authors:  M S Rajan; F D Bremner; P Riordan-Eva
Journal:  J R Soc Med       Date:  2002-10       Impact factor: 18.000

View more
  5 in total

1.  [Current state of pupil-based diagnostics for glaucomatous optic neuropathy].

Authors:  K Skorkovská; U Schiefer; B Wilhelm; H Wilhelm
Journal:  Ophthalmologe       Date:  2012-04       Impact factor: 1.059

2.  New approach for the glaucoma detection with pupil perimetry.

Authors:  Ken Asakawa; Nobuyuki Shoji; Hitoshi Ishikawa; Kimiya Shimizu
Journal:  Clin Ophthalmol       Date:  2010-07-21

3.  Tests for malingering in ophthalmology.

Authors:  Ali Ihsan Incesu
Journal:  Int J Ophthalmol       Date:  2013-10-18       Impact factor: 1.779

4.  Chromatic Pupil Campimetry Reveals Functional Defects in Exudative Age-Related Macular Degeneration with Differences Related to Disease Activity.

Authors:  Carina Kelbsch; Jakob Lange; Helmut Wilhelm; Barbara Wilhelm; Tobias Peters; Melanie Kempf; Laura Kuehlewein; Krunoslav Stingl
Journal:  Transl Vis Sci Technol       Date:  2020-05-11       Impact factor: 3.283

5.  Comparison of unifocal, flicker, and multifocal pupil perimetry methods in healthy adults.

Authors:  Brendan L Portengen; Giorgio L Porro; Saskia M Imhof; Marnix Naber
Journal:  J Vis       Date:  2022-08-01       Impact factor: 2.004

  5 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.