Literature DB >> 19096390

Regulation of T-helper-cell lineage development by osteopontin: the inside story.

Harvey Cantor1, Mari L Shinohara.   

Abstract

Studies of osteopontin (OPN)-dependent regulation of immune responses have focused on the cytokine activities of the secreted form of this protein. Recent evidence has revealed that an intracellular form of OPN expressed by dendritic cells regulates the expression of pro-inflammatory cytokines and the differentiation of T helper (T(H))-cell lineages. In this Opinion article, we discuss the properties of both OPN isoforms and their respective contributions to the immune response. We propose that cell-type-specific expression of secreted and intracellular OPN regulates the development of distinct effector T(H) cells, including that of T(H)1 and T(H)17 cells.

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Year:  2009        PMID： 19096390      PMCID： PMC2696694          DOI： 10.1038/nri2460

Source DB:  PubMed          Journal:  Nat Rev Immunol        ISSN： 1474-1733            Impact factor:   53.106


  61 in total

1.  Dendritic cells respond to influenza virus through TLR7- and PKR-independent pathways.

Authors:  Winfried Barchet; Anne Krug; Marina Cella; Celeste Newby; Jens A A Fischer; Andrzej Dzionek; Andrew Pekosz; Marco Colonna
Journal:  Eur J Immunol       Date:  2005-01       Impact factor: 5.532

2.  IL-4, IL-5 and IL-10 are not required for the control of M. bovis-BCG infection in mice.

Authors:  K J Erb; J Kirman; B Delahunt; W Chen; G Le Gros
Journal:  Immunol Cell Biol       Date:  1998-02       Impact factor: 5.126

3.  Implication of allelic polymorphism of osteopontin in the development of lupus nephritis in MRL/lpr mice.

Authors:  Tatsuhiko Miyazaki; Masao Ono; Wei-Min Qu; Ming-Cai Zhang; Shiro Mori; Shuichi Nakatsuru; Yusuke Nakamura; Tatsuya Sawasaki; Yaeta Endo; Masato Nose
Journal:  Eur J Immunol       Date:  2005-05       Impact factor: 5.532

4.  T-bet-dependent expression of osteopontin contributes to T cell polarization.

Authors:  Mari L Shinohara; Marianne Jansson; Eun Sook Hwang; Miriam B F Werneck; Laurie H Glimcher; Harvey Cantor
Journal:  Proc Natl Acad Sci U S A       Date:  2005-11-14       Impact factor: 11.205

5.  The cytokine osteopontin modulates the severity of rotavirus diarrhea.

Authors:  Ellen E Rollo; Scott J Hempson; Ajay Bansal; Ernest Tsao; Iman Habib; Susan R Rittling; David T Denhardt; Erich R Mackow; Robert D Shaw
Journal:  J Virol       Date:  2005-03       Impact factor: 5.103

6.  Osteopontin expression is essential for interferon-alpha production by plasmacytoid dendritic cells.

Authors:  Mari L Shinohara; Linrong Lu; Jing Bu; Miriam B F Werneck; Koichi S Kobayashi; Laurie H Glimcher; Harvey Cantor
Journal:  Nat Immunol       Date:  2006-04-09       Impact factor: 25.606

7.  Osteopontin is not required for the development of Th1 responses and viral immunity.

Authors:  Brian Abel; Stefan Freigang; Martin F Bachmann; Ursula Boschert; Manfred Kopf
Journal:  J Immunol       Date:  2005-11-01       Impact factor: 5.422

8.  Borrelia burgdorferi, an extracellular pathogen, circumvents osteopontin in inducing an inflammatory cytokine response.

Authors:  Kathleen Craig-Mylius; Georg F Weber; Jenifer Coburn; Lisa Glickstein
Journal:  J Leukoc Biol       Date:  2005-02-04       Impact factor: 4.962

9.  Osteopontin participates in Th1-mediated host resistance against nonlethal malaria parasite Plasmodium chabaudi chabaudi infection in mice.

Authors:  Yoshimasa Maeno; Shusuke Nakazawa; Naoki Yamamoto; Masanori Shinzato; Shigeo Nagashima; Kumiko Tanaka; Jun Sasaki; Susan R Rittling; David T Denhardt; Toshimitsu Uede; Koki Taniguchi
Journal:  Infect Immun       Date:  2006-04       Impact factor: 3.441

10.  Two single-nucleotide polymorphisms in the 5' and 3' ends of the osteopontin gene contribute to susceptibility to systemic lupus erythematosus.

Authors:  S D'Alfonso; N Barizzone; M Giordano; A Chiocchetti; C Magnani; L Castelli; M Indelicato; F Giacopelli; M Marchini; R Scorza; M G Danieli; M Cappelli; S Migliaresi; B Bigliardo; M G Sabbadini; E Baldissera; M Galeazzi; G D Sebastiani; G Minisola; R Ravazzolo; U Dianzani; P Momigliano-Richiardi
Journal:  Arthritis Rheum       Date:  2005-02
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  54 in total

1.  ECM components guide IL-10 producing regulatory T-cell (TR1) induction from effector memory T-cell precursors.

Authors:  Paul L Bollyky; Rebecca P Wu; Ben A Falk; James D Lord; S Alice Long; Anton Preisinger; Brandon Teng; Gregory E Holt; Nathan E Standifer; Kathleen R Braun; Cindy Fang Xie; Peter L Samuels; Robert B Vernon; John A Gebe; Thomas N Wight; Gerald T Nepom
Journal:  Proc Natl Acad Sci U S A       Date:  2011-04-25       Impact factor: 11.205

Review 2.  Intracellular osteopontin (iOPN) and immunity.

Authors:  Makoto Inoue; Mari L Shinohara
Journal:  Immunol Res       Date:  2011-04       Impact factor: 2.829

3.  The dual role of osteopontin in acetaminophen hepatotoxicity.

Authors:  Chun-yan He; Bei-bei Liang; Xiao-yu Fan; Lei Cao; Rui Chen; Ya-jun Guo; Jian Zhao
Journal:  Acta Pharmacol Sin       Date:  2012-06-25       Impact factor: 6.150

4.  Aire controls mesenchymal stem cell-mediated suppression in chronic colitis.

Authors:  Biju Parekkadan; Anne L Fletcher; Matthew Li; Melissa Y Tjota; Angelique Bellemare-Pelletier; Jack M Milwid; Je-Wook Lee; Martin L Yarmush; Shannon J Turley
Journal:  Mol Ther       Date:  2011-09-27       Impact factor: 11.454

5.  Discovery and verification of osteopontin and Beta-2-microglobulin as promising markers for staging human African trypanosomiasis.

Authors:  Natalia Tiberti; Alexandre Hainard; Veerle Lejon; Xavier Robin; Dieudonné Mumba Ngoyi; Natacha Turck; Enock Matovu; John Enyaru; Joseph Mathu Ndung'u; Alexander Scherl; Loïc Dayon; Jean-Charles Sanchez
Journal:  Mol Cell Proteomics       Date:  2010-08-19       Impact factor: 5.911

6.  Polymorphism in Osteopontin Gene (SPP1) Is Associated with Asthma and Related Phenotypes in a Puerto Rican Population.

Authors:  Mehrdad Arjomandi; Josh M Galanter; Shweta Choudhry; Celeste Eng; Donglei Hu; Kenneth Beckman; Rocío Chapela; José R Rodríguez-Santana; William Rodríguez-Cintrón; Jean Ford; Pedro C Avila; Esteban G Burchard
Journal:  Pediatr Allergy Immunol Pulmonol       Date:  2011-12       Impact factor: 1.349

Review 7.  Extracellular Matrix-Based Strategies for Immunomodulatory Biomaterials Engineering.

Authors:  Andrew T Rowley; Raji R Nagalla; Szu-Wen Wang; Wendy F Liu
Journal:  Adv Healthc Mater       Date:  2019-02-04       Impact factor: 9.933

8.  Antigen-specific induction of osteopontin contributes to the chronification of allergic contact dermatitis.

Authors:  Anne M Seier; Andreas C Renkl; Guido Schulz; Tanja Uebele; Anca Sindrilaru; Sebastian Iben; Lucy Liaw; Shigeyuki Kon; Toshimitsu Uede; Johannes M Weiss
Journal:  Am J Pathol       Date:  2009-12-11       Impact factor: 4.307

9.  Increased circulating Th17 cell populations and elevated CSF osteopontin and IL-17 concentrations in patients with Guillain-Barré syndrome.

Authors:  Rong Kun Han; Yue Feng Cheng; Shan Shan Zhou; Hong Guo; Rui Dong He; Li Jun Chi; Li Ming Zhang
Journal:  J Clin Immunol       Date:  2013-11-12       Impact factor: 8.317

10.  Neutralization of Osteopontin Ameliorates Acute Lung Injury Induced by Intestinal Ischemia-Reperfusion.

Authors:  Yohei Hirano; Monowar Aziz; Weng-Lang Yang; Mahendar Ochani; Ping Wang
Journal:  Shock       Date:  2016-10       Impact factor: 3.454
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