Literature DB >> 19095000

Molecular mechanisms of testosterone action in spermatogenesis.

William H Walker1.   

Abstract

Testosterone is required for the maturation of male germ cells, the production of sperm and thus male fertility. However, the mechanisms by which testosterone regulates spermatogenic processes have not been well defined. In this review, classical and non-classical pathways of testosterone signaling in the Sertoli cells of the testis are discussed in relation to testosterone-regulated processes that are required for spermatogenesis.

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Year:  2008        PMID： 19095000     DOI： 10.1016/j.steroids.2008.11.017

Source DB:  PubMed          Journal:  Steroids        ISSN： 0039-128X            Impact factor:   2.668


  40 in total

Review 1.  A local autocrine axis in the testes that regulates spermatogenesis.

Authors:  C Yan Cheng; Dolores D Mruk
Journal:  Nat Rev Endocrinol       Date:  2010-07       Impact factor: 43.330

2.  Plasticity of the reproductive axis caused by social status change in an african cichlid fish: II. testicular gene expression and spermatogenesis.

Authors:  Karen P Maruska; Russell D Fernald
Journal:  Endocrinology       Date:  2010-11-17       Impact factor: 4.736

3.  Interactions of laminin β3 fragment with β1-integrin receptor: A revisit of the apical ectoplasmic specialization-blood-testis-barrier-hemidesmosome functional axis in the testis.

Authors:  C Yan Cheng; Pearl Py Lie; Ka-Wai Mok; Yan-Ho Cheng; Elissa Wp Wong; Jayakanthan Mannu; Premendu P Mathur; Helen H N Yan; Dolores D Mruk
Journal:  Spermatogenesis       Date:  2011-07-01

4.  Testosterone signaling and the regulation of spermatogenesis.

Authors:  William H Walker
Journal:  Spermatogenesis       Date:  2011-04

5.  Reproductive biology: bone returns the favour.

Authors:  Sonya M Schuh-Huerta; Renee A Reijo Pera
Journal:  Nature       Date:  2011-04-07       Impact factor: 49.962

6.  An "endocrine function of" bone to pick: starting with males.

Authors:  Allan Z Zhao; Dongming Su
Journal:  Protein Cell       Date:  2011-03       Impact factor: 14.870

7.  A new analysis of testicular proteins through integrative bioinformatics.

Authors:  Liu Fu-Jun; Wang Hai-Yan; Li Jian-Yuan
Journal:  Mol Biol Rep       Date:  2011-07-16       Impact factor: 2.316

8.  Deregulated hepatic metabolism exacerbates impaired testosterone production in Mrp4-deficient mice.

Authors:  Jessica A Morgan; Satish B Cheepala; Yao Wang; Geoff Neale; Masashi Adachi; Deepa Nachagari; Mark Leggas; Wenchen Zhao; Kelli Boyd; Raman Venkataramanan; John D Schuetz
Journal:  J Biol Chem       Date:  2012-02-28       Impact factor: 5.157

Review 9.  Male reproductive health and prostate cancer risk.

Authors:  Thomas J Walsh
Journal:  Curr Opin Urol       Date:  2011-11       Impact factor: 2.309

10.  Seasonal variations of melatonin in ram seminal plasma are correlated to those of testosterone and antioxidant enzymes.

Authors:  Adriana Casao; Igor Cebrián; Mayra Eoda Asumpção; Rosaura Pérez-Pé; José A Abecia; Fernando Forcada; José A Cebrián-Pérez; Teresa Muiño-Blanco
Journal:  Reprod Biol Endocrinol       Date:  2010-06-11       Impact factor: 5.211
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