| Literature DB >> 19090698 |
Liza S Fernandez1, Malcolm S Buchanan, Anthony R Carroll, Yun Jiang Feng, Ronald J Quinn, Vicky M Avery.
Abstract
With the aim of finding new natural product antimalarials, the novel indole alkaloids flinderole A-C were found to have selective antimalarial activities with IC(50) values between 0.15-1.42 microM. Flinderole A was isolated from the Australian plant Flindersia acuminata and flinderoles B and C from the Papua New Guinean plant F. amboinensis. Flinderoles A-C contain an unprecedented rearranged skeleton compared to their related isomers of the borreverine class of compounds.Entities:
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Year: 2009 PMID： 19090698 DOI： 10.1021/ol802506n
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005