Literature DB >> 19088525

Pneumonia in the elderly: a review of the epidemiology, pathogenesis, microbiology, and clinical features.

Carol P Chong1, Philip R Street.   

Abstract

Pneumonia is a common and important disease in the elderly. The incidence is expected to rise as the population ages, and, therefore, it will become an increasingly significant problem in hospitals and the community. A comprehensive literature review was performed in order to look at the characteristics of pneumonia in the elderly population. In particular, the epidemiology, etiology and pathogenesis--including risk factors, microbiology, and clinical features--were evaluated. While aging causes physiological changes which make elderly patients more susceptible to pneumonia, it was found that comorbidities, rather than age, are also an important risk factor. The most common micro-organism responsible for pneumonia is Streptococcus pneumoniae, but other organisms need to be considered, depending on the environment of presentation. Elderly patients are more likely than younger adults to present with an absence of fever and an altered mental state. Nursing home residents tend to present with more atypical and less characteristic symptoms.

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Year:  2008        PMID: 19088525     DOI: 10.1097/SMJ.0b013e318181d5b5

Source DB:  PubMed          Journal:  South Med J        ISSN: 0038-4348            Impact factor:   0.954


  45 in total

1.  Dysregulated inflammation as a risk factor for pneumonia in the elderly.

Authors:  Angela R Boyd; Carlos J Orihuela
Journal:  Aging Dis       Date:  2011-12       Impact factor: 6.745

2.  Postoperative adverse outcomes in surgical patients with dementia: a retrospective cohort study.

Authors:  Chaur-Jong Hu; Chien-Chang Liao; Chuen-Chau Chang; Chih-Hsiung Wu; Ta-Liang Chen
Journal:  World J Surg       Date:  2012-09       Impact factor: 3.352

Review 3.  Modulation of connexin signaling by bacterial pathogens and their toxins.

Authors:  Liesbeth Ceelen; Freddy Haesebrouck; Tamara Vanhaecke; Vera Rogiers; Mathieu Vinken
Journal:  Cell Mol Life Sci       Date:  2011-06-09       Impact factor: 9.261

Review 4.  Older but Not Wiser: the Age-Driven Changes in Neutrophil Responses during Pulmonary Infections.

Authors:  Shaunna R Simmons; Manmeet Bhalla; Sydney E Herring; Essi Y I Tchalla; Elsa N Bou Ghanem
Journal:  Infect Immun       Date:  2021-03-17       Impact factor: 3.441

5.  A1 adenosine receptor signaling reduces Streptococcus pneumoniae adherence to pulmonary epithelial cells by targeting expression of platelet-activating factor receptor.

Authors:  Manmeet Bhalla; Jun Hui Yeoh; Claire Lamneck; Sydney E Herring; Essi Y I Tchalla; Lauren R Heinzinger; John M Leong; Elsa N Bou Ghanem
Journal:  Cell Microbiol       Date:  2019-11-20       Impact factor: 3.715

Review 6.  Elderly patients with community-acquired pneumonia: optimal treatment strategies.

Authors:  Ulrich Thiem; Hans-Jürgen Heppner; Ludger Pientka
Journal:  Drugs Aging       Date:  2011-07-01       Impact factor: 3.923

7.  Impact of sarcopenia on diaphragm muscle fatigue.

Authors:  Matthew J Fogarty; Carlos B Mantilla; Gary C Sieck
Journal:  Exp Physiol       Date:  2019-04-22       Impact factor: 2.969

Review 8.  Taking stock of infections and antibiotic resistance in the elderly and long-term care facilities: A survey of existing and upcoming challenges.

Authors:  S Augustine; R A Bonomo
Journal:  Eur J Microbiol Immunol (Bp)       Date:  2011-09-09

9.  Testing Anti-Pneumococcal Antibody Function Using Bacteria and Primary Neutrophils.

Authors:  Manmeet Bhalla; Shaunna R Simmons; Essi Y I Tchalla; Elsa N Bou Ghanem
Journal:  Methods Mol Biol       Date:  2021

10.  Predictors of pneumococcal vaccination among older adults with pneumonia: findings from the Community Acquired Pneumonia Impact Study.

Authors:  Paul Krueger; Oona St Amant; Mark Loeb
Journal:  BMC Geriatr       Date:  2010-06-30       Impact factor: 3.921

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