Literature DB >> 24516724

Taking stock of infections and antibiotic resistance in the elderly and long-term care facilities: A survey of existing and upcoming challenges.

S Augustine1, R A Bonomo1.   

Abstract

Treating elderly patients with infections represents one of the greatest challenges to health-care providers. Older adults are the largest growing sector of the population and suffer excessively from infectious diseases such as pneumonia, urinary tract infections (UTIs), and skin and soft-tissue infections. Often because of disabilities, the elderly require treatment of infectious diseases in long-term care facilities (LTCFs). As a result of antibiotic use, LTCFs have become "reservoirs of resistance" and multi-drug resistant (MDR) pathogens are frequently recovered. Clinicians also need to be aware of the impairment of immune function and other emerging chronic infections (HIV, HCV) that are now present in the elderly. Despite vigilance regarding this issue, delays in diagnosis and initiation of therapy are common. This article reviews the changing landscape of infections in the elderly and the challenge these syndromes present in the context of an increasing older population that requires dedicated resources.

Entities:  

Year:  2011        PMID: 24516724      PMCID: PMC3906614          DOI: 10.1556/EuJMI.1.2011.3.2

Source DB:  PubMed          Journal:  Eur J Microbiol Immunol (Bp)        ISSN: 2062-509X


  77 in total

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4.  Outbreak of ceftazidime resistance caused by extended-spectrum beta-lactamases at a Massachusetts chronic-care facility.

Authors:  L B Rice; S H Willey; G A Papanicolaou; A A Medeiros; G M Eliopoulos; R C Moellering; G A Jacoby
Journal:  Antimicrob Agents Chemother       Date:  1990-11       Impact factor: 5.191

5.  Impact of influenza vaccination on seasonal mortality in the US elderly population.

Authors:  Lone Simonsen; Thomas A Reichert; Cecile Viboud; William C Blackwelder; Robert J Taylor; Mark A Miller
Journal:  Arch Intern Med       Date:  2005-02-14

Review 6.  Varicella-zoster virus.

Authors:  A M Arvin
Journal:  Clin Microbiol Rev       Date:  1996-07       Impact factor: 26.132

7.  Ceftazidime-resistant Klebsiella pneumoniae isolates recovered at the Cleveland Department of Veterans Affairs Medical Center.

Authors:  L B Rice; E C Eckstein; J DeVente; D M Shlaes
Journal:  Clin Infect Dis       Date:  1996-07       Impact factor: 9.079

8.  Effectiveness of influenza vaccine in the community-dwelling elderly.

Authors:  Kristin L Nichol; James D Nordin; David B Nelson; John P Mullooly; Eelko Hak
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9.  Poor immune responses to influenza vaccination in infants.

Authors:  Takuji Kumagai; Kazushige Nagai; Toyo Okui; Hiroyuki Tsutsumi; Nobuo Nagata; Shoki Yano; Tetsuo Nakayama; Yoshinobu Okuno; Hitoshi Kamiya
Journal:  Vaccine       Date:  2004-09-03       Impact factor: 3.641

10.  Age-related immune dysfunction in health and in human immunodeficiency virus (HIV) disease: association of age and HIV infection with naive CD8+ cell depletion, reduced expression of CD28 on CD8+ cells, and reduced thymic volumes.

Authors:  Robert C Kalayjian; Alan Landay; Richard B Pollard; Dennis D Taub; Barry H Gross; Isaac R Francis; Anne Sevin; Minya Pu; John Spritzler; Miriam Chernoff; Ann Namkung; Lawrence Fox; Ana Martinez; Karen Waterman; Susan A Fiscus; Beverly Sha; Debra Johnson; Stanley Slater; Frank Rousseau; Michael M Lederman
Journal:  J Infect Dis       Date:  2003-05-29       Impact factor: 5.226

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2.  Host gut resistome in Gulf War chronic multisymptom illness correlates with persistent inflammation.

Authors:  Dipro Bose; Somdatta Chatterjee; Ethan Older; Ratanesh Seth; Patricia Janulewicz; Punnag Saha; Ayan Mondal; Jeffrey M Carlson; Alan W Decho; Kimberly Sullivan; Nancy Klimas; Stephen Lasley; Jie Li; Saurabh Chatterjee
Journal:  Commun Biol       Date:  2022-06-07

3.  The epidemiology of carbapenem-non-susceptible Acinetobacter species in Europe: analysis of EARS-Net data from 2013 to 2017.

Authors:  Olaniyi Ayobami; Niklas Willrich; Beneditta Suwono; Tim Eckmanns; Robby Markwart
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4.  Comparing appropriateness of antibiotics for nursing home residents by setting of prescription initiation: a cross-sectional analysis.

Authors:  Michael Pulia; Michael Kern; Rebecca J Schwei; Manish N Shah; Emmanuel Sampene; Christopher J Crnich
Journal:  Antimicrob Resist Infect Control       Date:  2018-06-14       Impact factor: 4.887

5.  Population-level mathematical modeling of antimicrobial resistance: a systematic review.

Authors:  Anna Maria Niewiadomska; Bamini Jayabalasingham; Jessica C Seidman; Lander Willem; Bryan Grenfell; David Spiro; Cecile Viboud
Journal:  BMC Med       Date:  2019-04-24       Impact factor: 8.775

6.  The ongoing challenge of vancomycin-resistant Enterococcus faecium and Enterococcus faecalis in Europe: an epidemiological analysis of bloodstream infections.

Authors:  Olaniyi Ayobami; Niklas Willrich; Annicka Reuss; Tim Eckmanns; Robby Markwart
Journal:  Emerg Microbes Infect       Date:  2020-12       Impact factor: 7.163

7.  Antimicrobial-associated organ injury among the elderly: a systematic review and meta-analysis protocol.

Authors:  Tichawona Chinzowu; Sandipan Roy; Prasad S Nishtala
Journal:  BMJ Open       Date:  2022-02-11       Impact factor: 2.692

  7 in total

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