OBJECTIVES: To assess whether different genomic cell-free DNAs are equally abundant in the plasma of individual donors, and any relationship between DNA methylation and representation in plasma. DESIGN AND METHODS: The concentrations of DNA in plasma were determined by real-time PCR. RESULTS: Different DNA sequences were not equally represented. The relative abundances were similar in different donors. CONCLUSIONS: Different DNA sequences are not equally abundant in plasma, with no relationship between DNA methylation and abundance.
OBJECTIVES: To assess whether different genomic cell-free DNAs are equally abundant in the plasma of individual donors, and any relationship between DNA methylation and representation in plasma. DESIGN AND METHODS: The concentrations of DNA in plasma were determined by real-time PCR. RESULTS: Different DNA sequences were not equally represented. The relative abundances were similar in different donors. CONCLUSIONS: Different DNA sequences are not equally abundant in plasma, with no relationship between DNA methylation and abundance.
Authors: Janine Aucamp; Abel J Bronkhorst; Dimetrie L Peters; Hayley C Van Dyk; Francois H Van der Westhuizen; Piet J Pretorius Journal: Cell Mol Life Sci Date: 2017-03-18 Impact factor: 9.261
Authors: E S Ershova; E M Jestkova; A V Martynov; G V Shmarina; P E Umriukhin; L V Bravve; N V Zakharova; G P Kostyuk; D V Saveliev; M D Orlova; M Bogush; S I Kutsev; N N Veiko; S V Kostyuk Journal: Int J Genomics Date: 2019-08-05 Impact factor: 2.326
Authors: Catalina Trejo-Becerril; Enrique Pérez-Cárdenas; Lucía Taja-Chayeb; Philippe Anker; Roberto Herrera-Goepfert; Luis A Medina-Velázquez; Alfredo Hidalgo-Miranda; Delia Pérez-Montiel; Alma Chávez-Blanco; Judith Cruz-Velázquez; José Díaz-Chávez; Miguel Gaxiola; Alfonso Dueñas-González Journal: PLoS One Date: 2012-12-28 Impact factor: 3.240