Literature DB >> 19081996

Nitroxyl radicals as low toxic spin-labels for non-invasive magnetic resonance imaging of blood-brain barrier permeability for conventional therapeutics.

Zhivko Zhelev1, Rumiana Bakalova, Ichio Aoki, Ken-Ichiro Matsumoto, Veselina Gadjeva, Kazunori Anzai, Iwao Kanno.   

Abstract

The present study describes a novel non-radioactive methodology for in vivo non-invasive, real-time imaging of blood-brain barrier (BBB) permeability for conventional drugs, using nitroxyl radicals as spin-labels and magnetic resonance imaging (MRI).

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Year:  2008        PMID： 19081996     DOI： 10.1039/b816878d

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  7 in total

1.  Imaging of superoxide generation in the dopaminergic area of the brain in Parkinson's disease, using mito-TEMPO.

Authors:  Zhivko Zhelev; Rumiana Bakalova; Ichio Aoki; Dessislava Lazarova; Tsuneo Saga
Journal:  ACS Chem Neurosci       Date:  2013-09-16       Impact factor: 4.418

2.  Pro-organic radical contrast agents ("pro-ORCAs") for real-time MRI of pro-drug activation in biological systems.

Authors:  Hung V-T Nguyen; Alexandre Detappe; Peter Harvey; Nolan Gallagher; Clelia Mathieu; Michael P Agius; Oksana Zavidij; Wencong Wang; Yivan Jiang; Andrzej Rajca; Alan Jasanoff; Irene M Ghobrial; P Peter Ghoroghchian; Jeremiah A Johnson
Journal:  Polym Chem       Date:  2020-06-26       Impact factor: 5.582

3.  Feasibility of magnetic resonance redox imaging at low magnetic field: comparison at 1 T and 7 T.

Authors:  Mizuki Nakamura; Sayaka Shibata; Toshihide Yamasaki; Megumi Ueno; Ikuo Nakanishi; Ken-Ichiro Matsumoto; Tadashi Kamada; Ken-Ichi Yamada; Ichio Aoki
Journal:  Am J Transl Res       Date:  2017-10-15       Impact factor: 4.060

4.  Triply Loaded Nitroxide Brush-Arm Star Polymers Enable Metal-Free Millimetric Tumor Detection by Magnetic Resonance Imaging.

Authors:  Hung V-T Nguyen; Alexandre Detappe; Nolan M Gallagher; Hui Zhang; Peter Harvey; Changcun Yan; Clelia Mathieu; Matthew R Golder; Yivan Jiang; Maria Francesca Ottaviani; Alan Jasanoff; Andrzej Rajca; Irene Ghobrial; P Peter Ghoroghchian; Jeremiah A Johnson
Journal:  ACS Nano       Date:  2018-11-02       Impact factor: 15.881

5.  Biological evaluation of new potential anticancer agent for tumour imaging and radiotherapy by two methods: 99mTc-radiolabelling and EPR spectroscopy.

Authors:  Yanka Karamalakova; Krishna Chuttani; Rakesh Sharma; Antoaneta Zheleva; Veselina Gadjeva; Anil Mishra
Journal:  Biotechnol Biotechnol Equip       Date:  2014-11-25       Impact factor: 1.632

6.  Nitroxide-Based Macromolecular Contrast Agents with Unprecedented Transverse Relaxivity and Stability for Magnetic Resonance Imaging of Tumors.

Authors:  Hung V-T Nguyen; Qixian Chen; Joseph T Paletta; Peter Harvey; Yivan Jiang; Hui Zhang; Michael D Boska; M Francesca Ottaviani; Alan Jasanoff; Andrzej Rajca; Jeremiah A Johnson
Journal:  ACS Cent Sci       Date:  2017-07-12       Impact factor: 14.553

7.  Nitroxyl Radical as a Theranostic Contrast Agent in Magnetic Resonance Redox Imaging.

Authors:  Ken-Ichiro Matsumoto; Ikuo Nakanishi; Zhivko Zhelev; Rumiana Bakalova; Ichio Aoki
Journal:  Antioxid Redox Signal       Date:  2021-07-28       Impact factor: 8.401
  7 in total

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