Literature DB >> 1907777

Suppression of cell-mediated immunity by purified aflatoxin B1 in broiler chicks.

R C Ghosh1, H V Chauhan, G J Jha.   

Abstract

The effect of purified aflatoxin B1 on cell-mediated immunity (CMI) in broiler chicks was assessed using doses of 0.3 and 1 mg/kg feed from hatching to 6 weeks of age. Total lymphocyte and T lymphocyte counts and the 2,4-dinitrofluorobenzene skin sensitivity test, graft-versus-host reaction and nitroblue tetrazolium salt reduction tests were used to evaluate CMI. Both doses of aflatoxin B1, including the apparently nontoxic dose of 0.3 mg/kg feed, caused a significant (P less than 0.05) decline in CMI. The functional activity of splenic macrophages was decreased significantly (P less than 0.05) by both doses of the toxin.

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Year:  1991        PMID： 1907777     DOI： 10.1016/0165-2427(91)90138-3

Source DB:  PubMed          Journal:  Vet Immunol Immunopathol        ISSN： 0165-2427            Impact factor:   2.046


  8 in total

1.  Immunosuppression in broiler chicks fed aflatoxin and inoculated with fowl adenovirus serotype-4 (FAV-4) associated with hydropericardium syndrome.

Authors:  S B Shivachandra; R L Sah; S D Singh; J M Kataria; K Manimaran
Journal:  Vet Res Commun       Date:  2003-01       Impact factor: 2.459

2.  Influence of low levels of dietary aflatoxins on Eimeria tenella infections in broilers.

Authors:  Hany F Ellakany; Somaia S Abuakkada; Samah S Oda; Yasser Said El-Sayed
Journal:  Trop Anim Health Prod       Date:  2010-08-25       Impact factor: 1.559

3.  Modulation of the spleen transcriptome in domestic turkey (Meleagris gallopavo) in response to aflatoxin B1 and probiotics.

Authors:  Melissa S Monson; Robert E Settlage; Kristelle M Mendoza; Sumit Rawal; Hani S El-Nezami; Roger A Coulombe; Kent M Reed
Journal:  Immunogenetics       Date:  2015-01-20       Impact factor: 2.846

4.  Evaluation of Cellulosic Polymers and Curcumin to Reduce Aflatoxin B1 Toxic Effects on Performance, Biochemical, and Immunological Parameters of Broiler Chickens.

Authors:  Bruno Solis-Cruz; Daniel Hernandez-Patlan; Victor M Petrone; Karine P Pontin; Juan D Latorre; Eric Beyssac; Xochitl Hernandez-Velasco; Ruben Merino-Guzman; Casey Owens; Billy M Hargis; Raquel Lopez-Arellano; Guillermo Tellez-Isaias
Journal:  Toxins (Basel)       Date:  2019-02-16       Impact factor: 4.546

5.  Effects of aflatoxin B1 on the cell cycle distribution of splenocytes in chickens.

Authors:  Hang Li; Ke Guan; Zhicai Zuo; Fengyuan Wang; Xi Peng; Jing Fang; Hengmin Cui; Yi Zhou; Ping Ouyang; Gang Su; Zhengli Chen
Journal:  J Toxicol Pathol       Date:  2018-11-18       Impact factor: 1.628

6.  Association Between Aflatoxin B1 Albumin Adduct Levels and Tuberculosis Infection Among HIV+ Ghanaians.

Authors:  John Keenan; Pauline Jolly; Peter Preko; Joseph Baidoo; Jia-Sheng Wang; Timothy D Phillips; Jonathan H Williams; Gerald McGwin
Journal:  Arch Clin Microbiol       Date:  2011

7.  Transcriptional Profiling of Aflatoxin B1-Induced Oxidative Stress and Inflammatory Response in Macrophages.

Authors:  Jinglin Ma; Yanrong Liu; Yongpeng Guo; Qiugang Ma; Cheng Ji; Lihong Zhao
Journal:  Toxins (Basel)       Date:  2021-06-04       Impact factor: 4.546

8.  Differential Transcriptome Responses to Aflatoxin B₁ in the Cecal Tonsil of Susceptible and Resistant Turkeys.

Authors:  Kent M Reed; Kristelle M Mendoza; Roger A Coulombe
Journal:  Toxins (Basel)       Date:  2019-01-18       Impact factor: 4.546
  8 in total

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