Literature DB >> 19075684

Phage display derived therapeutic antibodies.

Holger Thie1, Torsten Meyer, Thomas Schirrmann, Michael Hust, Stefan Dübel.   

Abstract

This article gives an overview about the development of human therapeutic antibodies generated by phage display. After an introduction to the method, the focus is on approved antibodies and those currently in clinical trials, 14 of which are described in detail.

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Year:  2008        PMID: 19075684     DOI: 10.2174/138920108786786349

Source DB:  PubMed          Journal:  Curr Pharm Biotechnol        ISSN: 1389-2010            Impact factor:   2.837


  27 in total

1.  Comparing CDRH3 diversity captured from secondary lymphoid organs for the generation of recombinant human antibodies.

Authors:  Sophie Venet; Marie Kosco-Vilbois; Nicolas Fischer
Journal:  MAbs       Date:  2013-07-02       Impact factor: 5.857

2.  Ligand-directed profiling of organelles with internalizing phage libraries.

Authors:  Andrey S Dobroff; Roberto Rangel; Liliana Guzman-Roja; Carolina C Salmeron; Juri G Gelovani; Richard L Sidman; Cristian G Bologa; Tudor I Oprea; C Jeffrey Brinker; Renata Pasqualini; Wadih Arap
Journal:  Curr Protoc Protein Sci       Date:  2015-02-02

3.  A high-throughput platform for population reformatting and mammalian expression of phage display libraries to enable functional screening as full-length IgG.

Authors:  Xiaodong Xiao; Julie A Douthwaite; Yan Chen; Ben Kemp; Sara Kidd; Jennifer Percival-Alwyn; Alison Smith; Kate Goode; Bonnie Swerdlow; David Lowe; Herren Wu; William F Dall'Acqua; Partha S Chowdhury
Journal:  MAbs       Date:  2017-06-14       Impact factor: 5.857

Review 4.  Bacteriophage vehicles for phage display: biology, mechanism, and application.

Authors:  Walead Ebrahimizadeh; Masoumeh Rajabibazl
Journal:  Curr Microbiol       Date:  2014-03-18       Impact factor: 2.188

5.  SAROTUP: scanner and reporter of target-unrelated peptides.

Authors:  Jian Huang; Beibei Ru; Shiyong Li; Hao Lin; Feng-Biao Guo
Journal:  J Biomed Biotechnol       Date:  2010-03-21

6.  By-passing in vitro screening--next generation sequencing technologies applied to antibody display and in silico candidate selection.

Authors:  U Ravn; F Gueneau; L Baerlocher; M Osteras; M Desmurs; P Malinge; G Magistrelli; L Farinelli; M H Kosco-Vilbois; N Fischer
Journal:  Nucleic Acids Res       Date:  2010-09-15       Impact factor: 16.971

7.  Identification of immunogenic proteins and generation of antibodies against Salmonella Typhimurium using phage display.

Authors:  Torsten Meyer; Thomas Schirrmann; André Frenzel; Sebastian Miethe; Janin Stratmann-Selke; Gerald F Gerlach; Katrin Strutzberg-Minder; Stefan Dübel; Michael Hust
Journal:  BMC Biotechnol       Date:  2012-06-15       Impact factor: 2.563

Review 8.  Phage displayed peptides/antibodies recognizing growth factors and their tyrosine kinase receptors as tools for anti-cancer therapeutics.

Authors:  Roberto Ronca; Patrizia Benzoni; Angela De Luca; Elisabetta Crescini; Patrizia Dell'Era
Journal:  Int J Mol Sci       Date:  2012-04-24       Impact factor: 6.208

9.  Identification of a putative Crf splice variant and generation of recombinant antibodies for the specific detection of Aspergillus fumigatus.

Authors:  Mark Schütte; Philippe Thullier; Thibaut Pelat; Xenia Wezler; Philip Rosenstock; Dominik Hinz; Martina Inga Kirsch; Mike Hasenberg; Ronald Frank; Thomas Schirrmann; Matthias Gunzer; Michael Hust; Stefan Dübel
Journal:  PLoS One       Date:  2009-08-13       Impact factor: 3.240

10.  Detection of biomarkers using recombinant antibodies coupled to nanostructured platforms.

Authors:  Michael R Kierny; Thomas D Cunningham; Brian K Kay
Journal:  Nano Rev       Date:  2012-07-23
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