Literature DB >> 19075064

Theileria apicoplast as a target for chemotherapy.

Regina Lizundia1, Dirk Werling, Gordon Langsley, Stuart A Ralph.   

Abstract

Theileria parasites cause severe bovine disease and death in a large part of the world. These apicomplexan parasites possess a relic plastid (apicoplast), whose metabolic pathways include several promising drug targets. Putative inhibitors of these targets were screened, and we identified antiproliferative compounds that merit further characterization.

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Year:  2008        PMID： 19075064      PMCID： PMC2650513          DOI： 10.1128/AAC.00126-08

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  34 in total

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Authors:  M E Fichera; D S Roos
Journal:  Nature       Date:  1997-11-27       Impact factor: 49.962

4.  Thiostrepton binds to malarial plastid rRNA.

Authors:  B Clough; M Strath; P Preiser; P Denny; I R Wilson
Journal:  FEBS Lett       Date:  1997-04-07       Impact factor: 4.124

Review 5.  The piroplasms: life cycle and sexual stages.

Authors:  H Mehlhorn; E Shein
Journal:  Adv Parasitol       Date:  1984       Impact factor: 3.870

6.  Inhibitors of the nonmevalonate pathway of isoprenoid biosynthesis as antimalarial drugs.

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Journal:  Science       Date:  1999-09-03       Impact factor: 47.728

7.  Activity of fluoroquinolone antibiotics against Plasmodium falciparum in vitro.

Authors:  A A Divo; A C Sartorelli; C L Patton; F J Bia
Journal:  Antimicrob Agents Chemother       Date:  1988-08       Impact factor: 5.191

8.  Two distinct forms of the peridinin-chlorophyll a-protein from Amphidinium carterae.

Authors:  F P Sharples; P M Wrench; K Ou; R G Hiller
Journal:  Biochim Biophys Acta       Date:  1996-09-12

9.  Cost analysis of immunisation against east coast fever on smallholder dairy farms in Kenya.

Authors:  G R Muraguri; S K Mbogo; N McHardy; D P Kariuki
Journal:  Prev Vet Med       Date:  1998-03-27       Impact factor: 2.670

10.  Antimalarial activity in vitro of the glyoxalase I inhibitor diester, S-p-bromobenzylglutathione diethyl ester.

Authors:  P J Thornalley; M Strath; R J Wilson
Journal:  Biochem Pharmacol       Date:  1994-01-20       Impact factor: 5.858
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  20 in total

Review 1.  The malaria parasite Plasmodium falciparum: cell biological peculiarities and nutritional consequences.

Authors:  Stefan Baumeister; Markus Winterberg; Jude M Przyborski; Klaus Lingelbach
Journal:  Protoplasma       Date:  2009-11-25       Impact factor: 3.356

2.  A Toxoplasma gondii mutant highlights the importance of translational regulation in the apicoplast during animal infection.

Authors:  T Matthew Payne; Amanda J Payne; Laura J Knoll
Journal:  Mol Microbiol       Date:  2011-11-07       Impact factor: 3.501

3.  Isoprenoid metabolism in apicomplexan parasites.

Authors:  Leah Imlay; Audrey R Odom
Journal:  Curr Clin Microbiol Rep       Date:  2014-12-01

Review 4.  Lipid synthesis in protozoan parasites: a comparison between kinetoplastids and apicomplexans.

Authors:  Srinivasan Ramakrishnan; Mauro Serricchio; Boris Striepen; Peter Bütikofer
Journal:  Prog Lipid Res       Date:  2013-07-01       Impact factor: 16.195

Review 5.  The evolution, metabolism and functions of the apicoplast.

Authors:  Liting Lim; Geoffrey Ian McFadden
Journal:  Philos Trans R Soc Lond B Biol Sci       Date:  2010-03-12       Impact factor: 6.237

6.  The toxoplasma apicoplast phosphate translocator links cytosolic and apicoplast metabolism and is essential for parasite survival.

Authors:  Carrie F Brooks; Hanne Johnsen; Giel G van Dooren; Mani Muthalagi; San San Lin; Wolfgang Bohne; Karsten Fischer; Boris Striepen
Journal:  Cell Host Microbe       Date:  2009-12-31       Impact factor: 21.023

Review 7.  Current advances in detection and treatment of babesiosis.

Authors:  J Mosqueda; A Olvera-Ramirez; G Aguilar-Tipacamu; G J Canto
Journal:  Curr Med Chem       Date:  2012       Impact factor: 4.530

Review 8.  The apicomplexan plastid and its evolution.

Authors:  Shigeharu Sato
Journal:  Cell Mol Life Sci       Date:  2011-03-05       Impact factor: 9.261

9.  Fosmidomycin uptake into Plasmodium and Babesia-infected erythrocytes is facilitated by parasite-induced new permeability pathways.

Authors:  Stefan Baumeister; Jochen Wiesner; Armin Reichenberg; Martin Hintz; Sven Bietz; Omar S Harb; David S Roos; Maximilian Kordes; Johannes Friesen; Kai Matuschewski; Klaus Lingelbach; Hassan Jomaa; Frank Seeber
Journal:  PLoS One       Date:  2011-05-04       Impact factor: 3.240

10.  Sequencing of the smallest Apicomplexan genome from the human pathogen Babesia microti.

Authors:  Emmanuel Cornillot; Kamel Hadj-Kaddour; Amina Dassouli; Benjamin Noel; Vincent Ranwez; Benoît Vacherie; Yoann Augagneur; Virginie Brès; Aurelie Duclos; Sylvie Randazzo; Bernard Carcy; Françoise Debierre-Grockiego; Stéphane Delbecq; Karina Moubri-Ménage; Hosam Shams-Eldin; Sahar Usmani-Brown; Frédéric Bringaud; Patrick Wincker; Christian P Vivarès; Ralph T Schwarz; Theo P Schetters; Peter J Krause; André Gorenflot; Vincent Berry; Valérie Barbe; Choukri Ben Mamoun
Journal:  Nucleic Acids Res       Date:  2012-07-24       Impact factor: 16.971
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