Literature DB >> 19072252

Ascorbate recycling by erythrocytes during aging in humans.

Syed Ibrahim Rizvi1, Kanti Bhooshan Pandey, Rashmi Jha, Pawan Kumar Maurya.   

Abstract

Erythrocytes play a crucial role in recycling ascorbate in blood plasma. The erythrocyte ascorbate free radical (AFR) reductase is involved in the reduction of AFR to ascorbic acid (ASC) in the plasma. In the present study, we report an age-dependent increase in the activity of erythrocyte AFR reductase in humans that shows a significant positive correlation with the activity of plasma membrane redox system (PMRS). We explain the age-dependent increase in erythrocyte ASC recycling on the basis of a compensatory/protective mechanism that operates to maintain the ASC level in plasma and thereby minimize oxidative stress during aging.

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Year:  2009        PMID： 19072252     DOI： 10.1089/rej.2008.0787

Source DB:  PubMed          Journal:  Rejuvenation Res        ISSN： 1549-1684            Impact factor:   4.663


  10 in total

1.  Epigallocatechin-3-Gallate Protects Erythrocyte Ca(2+)-ATPase and Na(+)/K(+)-ATPase Against Oxidative Induced Damage During Aging in Humans.

Authors:  Prabhanshu Kumar; Pawan Kumar Maurya
Journal:  Adv Pharm Bull       Date:  2014-08-25

2.  Plant polyphenols as electron donors for erythrocyte plasma membrane redox system: validation through in silico approach.

Authors:  Rajesh Kumar Kesharwani; Durg Vijay Singh; Krishna Misra; Syed Ibrahim Rizvi
Journal:  Org Med Chem Lett       Date:  2012-04-04

3.  Supplementation of anti-oxidants in leucofiltered erythrocyte concentrates: assessment of morphological changes through scanning electron microscopy.

Authors:  Valeria Pallotta; Fabio Naro; Federica Gevi; Angelo D'Alessandro; Lello Zolla
Journal:  Blood Transfus       Date:  2014-06-05       Impact factor: 3.443

4.  Spectroscopic determination of intracellular quercetin uptake using erythrocyte model and its implications in human aging.

Authors:  Prabhanshu Kumar; Ridhima Wadhwa; Riya Gupta; Pranjal Chandra; Pawan Kumar Maurya
Journal:  3 Biotech       Date:  2018-11-26       Impact factor: 2.406

5.  Protective effect of catechin on pentachlorophenol-induced cytotoxicity and genotoxicity in isolated human blood cells.

Authors:  Nikhil Maheshwari; Riaz Mahmood
Journal:  Environ Sci Pollut Res Int       Date:  2020-02-08       Impact factor: 4.223

Review 6.  Markers of oxidative stress in erythrocytes and plasma during aging in humans.

Authors:  Kanti Bhooshan Pandey; Syed Ibrahim Rizvi
Journal:  Oxid Med Cell Longev       Date:  2010 Jan-Feb       Impact factor: 6.543

7.  Storing red blood cells with vitamin C and N-acetylcysteine prevents oxidative stress-related lesions: a metabolomics overview.

Authors:  Valeria Pallotta; Federica Gevi; Angelo D'alessandro; Lello Zolla
Journal:  Blood Transfus       Date:  2014-06-05       Impact factor: 3.443

8.  Protective effect of theaflavin on erythrocytes subjected to in vitro oxidative stress.

Authors:  Mahejabeen Fatima; Rajesh Kumar Kesharwani; Krishna Misra; Syed Ibrahim Rizvi
Journal:  Biochem Res Int       Date:  2013-12-21

9.  The Pro-Oxidant Activity of Red Wine Polyphenols Induces an Adaptive Antioxidant Response in Human Erythrocytes.

Authors:  Idolo Tedesco; Carmela Spagnuolo; Gian Luigi Russo; Maria Russo; Carmen Cervellera; Stefania Moccia
Journal:  Antioxidants (Basel)       Date:  2021-05-18

10.  Prospects of Vitamin C as an Additive in Plasma of Stored Blood.

Authors:  R Vani; R Soumya; H Carl; V A Chandni; K Neha; B Pankhuri; S Trishna; D P Vatsal
Journal:  Adv Hematol       Date:  2015-08-09
  10 in total

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