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Literature DB >> 19070572

HMGA2, microRNAs, and stem cell aging.

Abstract

Mammalian aging results from a replicative decline in the function of somatic stem cells and other self-renewing cells. Recent studies (Monzen et al., 2008; Nishino et al., 2008; Sanna et al., 2008; Weedon et al., 2008) link a chromatin-associated protein, HMGA2, to development, height, and mouse stem cell aging during late fetal development and young adulthood.

Entities: Disease Gene Species

Mesh：

Substances：
HMGA2 Protein
MicroRNAs

Year: 2008 PMID： 19070572 PMCID： PMC3725266 DOI： 10.1016/j.cell.2008.11.026

Source DB: PubMed Journal: Cell ISSN： 0092-8674 Impact factor: 41.582

20 in total

1. Identification and characterization of lin-28 homolog B (LIN28B) in human hepatocellular carcinoma.

Authors: Yingqiu Guo; Yongxin Chen; Hirotaka Ito; Akira Watanabe; Xijin Ge; Tatsuhiko Kodama; Hiroyuki Aburatani
Journal: Gene Date: 2006-07-28 Impact factor: 3.688

2. Deficiencies in DNA damage repair limit the function of haematopoietic stem cells with age.

Authors: Derrick J Rossi; David Bryder; Jun Seita; Andre Nussenzweig; Jan Hoeijmakers; Irving L Weissman
Journal: Nature Date: 2007-06-07 Impact factor: 49.962

3. Constitutional rearrangement of the architectural factor HMGA2: a novel human phenotype including overgrowth and lipomas.

Authors: Azra H Ligon; Steven D P Moore; Melissa A Parisi; Matthew E Mealiffe; David J Harris; Heather L Ferguson; Bradley J Quade; Cynthia C Morton
Journal: Am J Hum Genet Date: 2004-12-10 Impact factor: 11.025

4. A novel role for high-mobility group a proteins in cellular senescence and heterochromatin formation.

Authors: Masashi Narita; Masako Narita; Valery Krizhanovsky; Sabrina Nuñez; Agustin Chicas; Stephen A Hearn; Michael P Myers; Scott W Lowe
Journal: Cell Date: 2006-08-11 Impact factor: 41.582

5. The expression of a truncated HMGI-C gene induces gigantism associated with lipomatosis.

Authors: S Battista; V Fidanza; M Fedele; A J Klein-Szanto; E Outwater; H Brunner; M Santoro; C M Croce; A Fusco
Journal: Cancer Res Date: 1999-10-01 Impact factor: 12.701

Review 6. How stem cells age and why this makes us grow old.

Authors: Norman E Sharpless; Ronald A DePinho
Journal: Nat Rev Mol Cell Biol Date: 2007-09 Impact factor: 94.444

Review 7. Roles of HMGA proteins in cancer.

Authors: Alfredo Fusco; Monica Fedele
Journal: Nat Rev Cancer Date: 2007-12 Impact factor: 60.716

8. Mutation responsible for the mouse pygmy phenotype in the developmentally regulated factor HMGI-C.

Authors: X Zhou; K F Benson; H R Ashar; K Chada
Journal: Nature Date: 1995-08-31 Impact factor: 49.962

Review 9. Regulation of the INK4b-ARF-INK4a tumour suppressor locus: all for one or one for all.

Authors: Jesús Gil; Gordon Peters
Journal: Nat Rev Mol Cell Biol Date: 2006-09 Impact factor: 94.444

10. Hmga2 promotes neural stem cell self-renewal in young but not old mice by reducing p16Ink4a and p19Arf Expression.

Authors: Jinsuke Nishino; Injune Kim; Kiran Chada; Sean J Morrison
Journal: Cell Date: 2008-10-17 Impact factor: 41.582

66 in total

Review 1. Mechanisms of age-related cognitive change and targets for intervention: epigenetics.

Authors: Kenneth S Kosik; Peter R Rapp; Naftali Raz; Scott A Small; J David Sweatt; Li-Huei Tsai
Journal: J Gerontol A Biol Sci Med Sci Date: 2012-04-20 Impact factor: 6.053

2. Changes in interstitial cells of cajal with age in the human stomach and colon.

Authors: P J Gomez-Pinilla; S J Gibbons; M G Sarr; M L Kendrick; K Robert Shen; R R Cima; E J Dozois; D W Larson; T Ordog; M J Pozo; G Farrugia
Journal: Neurogastroenterol Motil Date: 2010-08-19 Impact factor: 3.598

3. Establishment of human trophoblast progenitor cell lines from the chorion.

Authors: Olga Genbacev; Matthew Donne; Mirhan Kapidzic; Matthew Gormley; Julie Lamb; Jacqueline Gilmore; Nicholas Larocque; Gabriel Goldfien; Tamara Zdravkovic; Michael T McMaster; Susan J Fisher
Journal: Stem Cells Date: 2011-09 Impact factor: 6.277

4. Aging and microRNA expression in human skeletal muscle: a microarray and bioinformatics analysis.

Authors: Micah J Drummond; John J McCarthy; Mala Sinha; Heidi M Spratt; Elena Volpi; Karyn A Esser; Blake B Rasmussen
Journal: Physiol Genomics Date: 2010-09-28 Impact factor: 3.107

5. Insights into the regulation of a common variant of HMGA2 associated with human height during embryonic development.

Authors: Yvonne Tay; Sabrina Peter; Isidore Rigoutsos; Paulette Barahona; Sohail Ahmed; Peter Dröge
Journal: Stem Cell Rev Rep Date: 2009-12 Impact factor: 5.739

Review 6. Biosafety features of lentiviral vectors.

Authors: Axel Schambach; Daniela Zychlinski; Birgitta Ehrnstroem; Christopher Baum
Journal: Hum Gene Ther Date: 2013-02 Impact factor: 5.695

Review 7. Causes, consequences, and reversal of immune system aging.

Authors: Encarnacion Montecino-Rodriguez; Beata Berent-Maoz; Kenneth Dorshkind
Journal: J Clin Invest Date: 2013-03-01 Impact factor: 14.808

8. Down-regulation of miR-320 associated with cancer progression and cell apoptosis via targeting Mcl-1 in cervical cancer.

Authors: Ting Zhang; Ping Zou; Tiejun Wang; Jingying Xiang; Jing Cheng; Daozhen Chen; Jianwei Zhou
Journal: Tumour Biol Date: 2016-01-11

9. Circulating cell-free high mobility group AT-hook 2 mRNA as a detection marker in the serum of colorectal cancer patients.

Authors: Sana Sahengbieke; Jian Wang; Xiangwei Li; Yuhong Wang; Maode Lai; Jingjing Wu
Journal: J Clin Lab Anal Date: 2017-09-26 Impact factor: 2.352

10. let-7 enhances osteogenesis and bone formation while repressing adipogenesis of human stromal/mesenchymal stem cells by regulating HMGA2.

Authors: Jianfeng Wei; Hongling Li; Shihua Wang; Tangping Li; Junfen Fan; Xiaolei Liang; Jing Li; Qin Han; Li Zhu; Linyuan Fan; Robert Chunhua Zhao
Journal: Stem Cells Dev Date: 2014-05-22 Impact factor: 3.272