Literature DB >> 19064979

Phase II study of an outpatient palliative care intervention in patients with metastatic cancer.

Matthew Follwell1, Debika Burman, Lisa W Le, Kristina Wakimoto, Dori Seccareccia, John Bryson, Gary Rodin, Camilla Zimmermann.   

Abstract

PURPOSE: Although there is increasing advocacy for timely symptom control in patients with cancer, few studies have assessed outpatient palliative care clinics. This study assessed prospectively the efficacy of an Oncology Palliative Care Clinic (OPCC) in improving patient symptom distress and satisfaction. PATIENTS AND METHODS: Eligible patients were new referrals to an OPCC, had metastatic cancer, were at least 18 years old, and were well enough and able to speak and read English sufficiently to provide informed consent and complete questionnaires. Patients received a consultation by a palliative care team. The primary end points of symptom control and patient satisfaction were assessed using the Edmonton Symptom Assessment Scale (ESAS) and patient-adapted Family Satisfaction with Advanced Cancer Care (FAMCARE) scale at baseline, 1 week, and 1 month. Initial and follow-up scores were compared using paired t tests.
RESULTS: Of 150 patients enrolled, 123 completed 1-week assessments, and 88 completed 4-week assessments. At baseline, the mean ESAS Distress Score (EDS) was 39.5. The mean improvement in EDS was 8.8 points (P < .0001) at 1 week and 7.0 points (P < .0001) at 1 month. Statistically significant improvements were observed for pain, fatigue, nausea, depression, anxiety, drowsiness, appetite, dyspnea, insomnia, and constipation at 1 week (all P < or = .005) and 1 month (all P < or = .05). The mean improvement in FAMCARE score was 6.1 points (P < .0001) at 1 week and 5.0 points (P < .0001) at 1 month.
CONCLUSION: This phase II study demonstrates efficacy of an OPCC for improvement of symptom control and patient satisfaction with care. Randomized controlled trials are indicated to further evaluate the effectiveness of specialized outpatient palliative care.

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Year:  2008        PMID: 19064979     DOI: 10.1200/JCO.2008.17.7568

Source DB:  PubMed          Journal:  J Clin Oncol        ISSN: 0732-183X            Impact factor:   44.544


  63 in total

1.  Update in palliative care--2011.

Authors:  Patricia F Harris; Robert M Arnold; Ursula K Braun; Erik Fromme; Rahwa Ghermay; Stephanie Harman; Robert L Jayes; Anne M Walling
Journal:  J Gen Intern Med       Date:  2011-11-30       Impact factor: 5.128

2.  Health care providers' use and knowledge of the Edmonton Symptom Assessment System (ESAS): is there a need to improve information and training?

Authors:  Daniela Carli Buttenschoen; Jarad Stephan; Sharon Watanabe; Cheryl Nekolaichuk
Journal:  Support Care Cancer       Date:  2013-09-13       Impact factor: 3.603

3.  Age and gender differences in symptom intensity and symptom clusters among patients with metastatic cancer.

Authors:  Winson Y Cheung; Lisa W Le; Lucia Gagliese; Camilla Zimmermann
Journal:  Support Care Cancer       Date:  2010-03-24       Impact factor: 3.603

4.  Factors associated with discharge disposition on an acute palliative care unit.

Authors:  David Hausner; Nanor Kevork; Ashley Pope; Breffni Hannon; John Bryson; Jenny Lau; Gary Rodin; Lisa W Le; Camilla Zimmermann
Journal:  Support Care Cancer       Date:  2018-05-30       Impact factor: 3.603

Review 5.  The Edmonton Symptom Assessment System 25 Years Later: Past, Present, and Future Developments.

Authors:  David Hui; Eduardo Bruera
Journal:  J Pain Symptom Manage       Date:  2016-12-29       Impact factor: 3.612

6.  Performance of the Family Satisfaction with the End-of-Life Care (FAMCARE) measure in an ethnically diverse cohort: psychometric analyses using item response theory.

Authors:  Jeanne A Teresi; Katherine Ornstein; Katja Ocepek-Welikson; Mildred Ramirez; Albert Siu
Journal:  Support Care Cancer       Date:  2013-10-05       Impact factor: 3.603

7.  Integrated outpatient palliative care for patients with advanced cancer: A systematic review and meta-analysis.

Authors:  Jessica J Fulton; Thomas W LeBlanc; Toni M Cutson; Kathryn N Porter Starr; Arif Kamal; Katherine Ramos; Caroline E Freiermuth; Jennifer R McDuffie; Andrzej Kosinski; Soheir Adam; Avishek Nagi; John W Williams
Journal:  Palliat Med       Date:  2018-11-29       Impact factor: 4.762

8.  Symptom burden and supportive care in patients with acute leukemia.

Authors:  Camilla Zimmermann; Dora Yuen; Ashley Mischitelle; Mark D Minden; Joseph M Brandwein; Aaron Schimmer; Lucia Gagliese; Christopher Lo; Anne Rydall; Gary Rodin
Journal:  Leuk Res       Date:  2013-03-11       Impact factor: 3.156

9.  Measuring patient satisfaction in oncology palliative care: psychometric properties of the FAMCARE-patient scale.

Authors:  Christopher Lo; Debika Burman; Gary Rodin; Camilla Zimmermann
Journal:  Qual Life Res       Date:  2009-06-10       Impact factor: 4.147

Review 10.  Palliative care reduces morbidity and mortality in cancer.

Authors:  Gabrielle B Rocque; James F Cleary
Journal:  Nat Rev Clin Oncol       Date:  2012-12-18       Impact factor: 66.675

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