Literature DB >> 19060726

Implications of formal alcohol screening in burn patients.

Joslyn M Albright1, Elizabeth J Kovacs, Richard L Gamelli, Carol R Schermer.   

Abstract

The purpose of this study was to screen burn patients for alcohol use disorders to identify those at increased risk for repeat injury and adverse effects of alcohol use. We examined associations of at-risk drinking and dependence symptoms as measured by a formal screening tool and blood alcohol concentration (BAC) to guide further screening, treatment, and research. We hypothesized that the majority of drinkers would not have symptoms of alcohol dependence, that BAC would be inadequate to screen for alcohol disorders, and that at-risk drinkers would be more likely to be unemployed and uninsured than healthy drinkers. Formal screening of English speakers, age 16 to 75, admitted to the burn service for over 24 hours was conducted for a 6-month period, using the Alcohol Use Disorders Identification Test. Of the 123 patients eligible for the study, 110 (89.4%) were approached for formal screening, four refused (3.6%), and 13 were missed (10.6%). BAC was obtained in 68 of 110 (61.8%); no patient who reported abstinence had a positive BAC. Of the 106 screened, 34.9% were nondrinkers, 11.3% drank daily or almost daily, and 28.3% binge drank at least monthly (>4 drinks per occasion for men, >3 for women). Of the patients who drank, only eight patients reported one or more sign of dependence in the last year (11.6%). For the group as a whole, 20.9% met Alcohol Use Disorders Identification Test criteria for at-risk drinking, with an average BAC of 39.8 mg/dl, (range 0-242 mg/dl). Using BAC of >or=80 mg/dl, only 5.6% of patients would have been identified as at-risk drinkers. Twenty-three percent of patients had no health insurance, 36% of whom were at-risk drinkers compared with 17.3% of insured patients (P < .05). For the group as a whole, 41.8% of patients were unemployed. At-risk drinking did not differ between employed and unemployed patients (24.6% vs 17.8%, P > .05). Among burn patients, formal alcohol screening identified that one in five patients is at risk for further problems from their drinking and that most at-risk drinkers are binge drinkers and do not show signs of dependency. Formal screening identified more at-risk drinkers than BAC. Implications of the screening findings are 1) because most burn patients who drink are binge but not dependent drinkers, alcohol withdrawal should be infrequent, and 2) animal models of alcohol use and burn injury should study acute intoxication and binge exposure. In addition, 3) we would expect burn patients to respond to brief interventions for alcohol use disorders similar to trauma and primary care patients.

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Year:  2009        PMID: 19060726      PMCID: PMC2920748          DOI: 10.1097/BCR.0b013e3181921f31

Source DB:  PubMed          Journal:  J Burn Care Res        ISSN: 1559-047X            Impact factor:   1.845


  22 in total

1.  Screening for problem drinking in older people referred to a mental health service: a comparison of CAGE and AUDIT.

Authors:  M Philpot; N Pearson; V Petratou; R Dayanandan; M Silverman; J Marshall
Journal:  Aging Ment Health       Date:  2003-05       Impact factor: 3.658

2.  Binge drinking, sensible drinking, and abstinence after alcohol-related vehicular crashes: the role of intervention versus screening.

Authors:  M S Sommers; J M Dyehouse; S R Howe
Journal:  Annu Proc Assoc Adv Automot Med       Date:  2001

3.  Effects of alcohol intoxication on the initial assessment of trauma patients.

Authors:  G J Jurkovich; F P Rivara; J G Gurney; D Seguin; C L Fligner; M Copass
Journal:  Ann Emerg Med       Date:  1992-06       Impact factor: 5.721

4.  Screening adolescents for problem drinking: performance of brief screens against DSM-IV alcohol diagnoses.

Authors:  T Chung; S M Colby; N P Barnett; D J Rohsenow; A Spirito; P M Monti
Journal:  J Stud Alcohol       Date:  2000-07

5.  Epidemiology of burns. The burn-prone patient.

Authors:  J D MacArthur; F D Moore
Journal:  JAMA       Date:  1975-01-20       Impact factor: 56.272

6.  Detection of acute alcohol intoxication and chronic alcohol dependence by trauma center staff.

Authors:  L M Gentilello; A Villaveces; R R Ries; K S Nason; E Daranciang; D M Donovan; M Copass; G J Jurkovich; F P Rivara
Journal:  J Trauma       Date:  1999-12

7.  A longitudinal study of former trauma center patients: the association between toxicology status and subsequent injury mortality.

Authors:  P C Dischinger; K A Mitchell; J A Kufera; C A Soderstrom; A B Lowenfels
Journal:  J Trauma       Date:  2001-11

8.  Comparison of trauma center patient self-reports and proxy reports on the Alcohol Use Identification Test (AUDIT).

Authors:  Dennis M Donovan; Chris W Dunn; Frederick P Rivara; Gregory J Jurkovich; Richard R Ries; Larry M Gentilello
Journal:  J Trauma       Date:  2004-04

9.  Urban trauma: a chronic recurrent disease.

Authors:  D W Sims; B A Bivins; F N Obeid; H M Horst; V J Sorensen; J J Fath
Journal:  J Trauma       Date:  1989-07

10.  The effects of preexisting medical comorbidities on mortality and length of hospital stay in acute burn injury: evidence from a national sample of 31,338 adult patients.

Authors:  Brett D Thombs; Vijay A Singh; Jill Halonen; Alfa Diallo; Stephen M Milner
Journal:  Ann Surg       Date:  2007-04       Impact factor: 12.969

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  15 in total

1.  6-Formylindolo (3, 2-b) Carbazole (FICZ)-mediated protection of gut barrier is dependent on T cells in a mouse model of alcohol combined with burn injury.

Authors:  Xiaoling Li; Marisa E Luck; Adam M Hammer; Abigail R Cannon; Mashkoor A Choudhry
Journal:  Biochim Biophys Acta Mol Basis Dis       Date:  2020-07-22       Impact factor: 5.187

Review 2.  Organ-specific inflammation following acute ethanol and burn injury.

Authors:  Melanie D Bird; Elizabeth J Kovacs
Journal:  J Leukoc Biol       Date:  2008-03-24       Impact factor: 4.962

3.  The influence of substance misuse on clinical outcomes following burn.

Authors:  Sarah Rehou; Stephanie Mason; Jessie MacDonald; Ruxandra Pinto; Marc G Jeschke
Journal:  Burns       Date:  2017-05-12       Impact factor: 2.744

4.  Comparison of Objective Screening and Self-Report for Alcohol and Drug Use in Traumatically Injured Patients.

Authors:  Lauren M Sakai; Thomas J Esposito; Hieu H Ton-That; Ellen C Omi; Elizabeth J Kovacs; Carol R Schermer
Journal:  Alcohol Treat Q       Date:  2012-10-12

5.  Interleukin-22 modulates gut epithelial and immune barrier functions following acute alcohol exposure and burn injury.

Authors:  Juan L Rendon; Xiaoling Li; Suhail Akhtar; Mashkoor A Choudhry
Journal:  Shock       Date:  2013-01       Impact factor: 3.454

Review 6.  Laboratory models available to study alcohol-induced organ damage and immune variations: choosing the appropriate model.

Authors:  Nympha B D'Souza El-Guindy; Elizabeth J Kovacs; Philippe De Witte; Claudia Spies; John M Littleton; Willem J S de Villiers; Amanda J Lott; Timothy P Plackett; Nadine Lanzke; Gary G Meadows
Journal:  Alcohol Clin Exp Res       Date:  2010-06-25       Impact factor: 3.455

7.  Adipose inflammation and macrophage infiltration after binge ethanol and burn injury.

Authors:  Yuanyuan Qin; Jillian L Hamilton; Melanie D Bird; Michael M Chen; Luis Ramirez; Anita Zahs; Elizabeth J Kovacs; Liza Makowski
Journal:  Alcohol Clin Exp Res       Date:  2013-08-01       Impact factor: 3.455

Review 8.  Intestine immune homeostasis after alcohol and burn injury.

Authors:  Xiaoling Li; Adam M Hammer; Juan L Rendon; Mashkoor A Choudhry
Journal:  Shock       Date:  2015-06       Impact factor: 3.454

9.  Implications of alcohol intoxication at the time of burn and smoke inhalation injury: an epidemiologic and clinical analysis.

Authors:  Christopher S Davis; Thomas J Esposito; Anna G Palladino-Davis; Karen Rychlik; Carol R Schermer; Richard L Gamelli; Elizabeth J Kovacs
Journal:  J Burn Care Res       Date:  2013 Jan-Feb       Impact factor: 1.845

10.  The role of aryl hydrocarbon receptor in interleukin-23-dependent restoration of interleukin-22 following ethanol exposure and burn injury.

Authors:  Juan L Rendon; Xiaoling Li; Aleah L Brubaker; Elizabeth J Kovacs; Richard L Gamelli; Mashkoor A Choudhry
Journal:  Ann Surg       Date:  2014-03       Impact factor: 12.969

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